2013-12-30

endothialial dysfunction and muscle cramps

12.30: summary:
. I've been more prone to leg cramping and edema,
as if something is clogging the leg's circulation
thereby depriving it of relaxing magnesium .
. it got much worse eating under-treated olives,
but that may have been due to increasing arginine
since that could have worsened a certain condition
that in turn worsens auto-immune activity .

4: web.med/muscle cramps:
nighttime-leg-cramps
.  cramps may occur because of decreased amounts of
minerals, such as calcium, potassium, and magnesium,
usually caused by blood flow problems
(peripheral arterial disease),
. things that can make limb circulation worse:
# Exposure to cold temperatures
# Other medical conditions, such as
kidney disease, thyroid disease, and multiple sclerosis;
# Taking certain medicines, such as antipsychotics,
birth control pills, diuretics, statins, and steroids.
27: Endothelial dysfunction and hypothyroidism:
. thyroid disease related to poor circulation?
what about Endothelial dysfunction and hypothyroidism?
. Subclinical hypothyroidism (SH) is defined as
normal serum free T4 and free T3 levels
and increased serum TSH levels.
. SH accelerates endothelial dysfunction;
it is associated with chronic inflammation
(C reactive protein)
and simultaneously reduces the bioavailability of
nitric oxide to blood vessels;
SH increases the expression of angiotensin receptor,
that causes blood vessels to contract,
thereby increasing the pressure within the vessels .
Furthermore, replacement therapy
seems to improve all these aspects.
Endothelial dysfunction and hypothyroidism/reverse t3:
it could be thyroid resistance;
if I'm getting too much t4,
then it could be converted into reverse t3,
which is creating a thyroid deficiency
that is creating
markers of chronic inflammation (C reactive protein)
and simultaneously reducing the bioavailability of
nitric oxide to blood vessels
which results in endothelial dysfunction .

on the other hand:
C-reactive protein is also elevated in
most prostatitis cases .
Men with chronic prostatitis
or chronic pelvic pain syndrome
have evidence of increased arterial stiffness
and vascular endothelial dysfunction .