"reversible" Monoamine Oxidase A inhibitor:
. related to dopamine?
Tribulus extracts may contain "reversible"
inhibitors of Monoamine Oxidase A .
MAO-A can selectively metabolize. lef member suggests tribestan .
adrenaline, noradrenaline, serotonin,
and dopamine to inactive compounds.
Tribulus contains Harmine,
a short-acting, "reversible" MAOI-A inhibitor
The inhibition of MAO-A prevents the degradation of
adrenaline, noradrenaline, serotonin, and dopamine
and the result can be increased mood,
alleviation of depression and more energy.
High dopamine levels can stimulate the pituitary gland
to release lutenizing hormone (LH)
which leads to an increase in testosterone levels
and thus elevating libido, another mood enhancer.
Harmine is "reversible" because it
does not bind permanently to MAO-A,
thus is not as contraindicated with
tyramine-containing foods (cheese, red wine, etc)
as irreversible MAOI's,
nor does harmine raise levels of tyramine per se
since it allows tyramine to be metabolized.
The short-acting and non-permanency
of it's binding capabilities means that
the anti-depressive effects of harmine
usually cease 24-48 hours after stopping therapy.
. with a half-life of 2.5 hours,
several doses are necessary;
eg 3 * 750 ... 1,500 mg
of standardized 45% steroidal sapponins.
tribulus at Beyond A Century:
(bac's 1kg, 100g, High-Protodiocin 50g).
[. this was added to the health store page
under performance/mood enhanced .]