liver-glucose reducer lowers inflammation

5.14: news.health/liver-glucose reducer lowers inflammation:

"Metformin's strong anti-inflammatory properties
by activating an enzyme called AMPK,
which in turn damps down
the activity of the protein NF-kappa B.
The inhibition of that suppresses the production of
inflammatory signaling molecules
-- cytokines and chemokines --
needed to initiate and sustain uveitis.
Uveitis causes 10 to 15 % of all blindness in the USA
and even higher proportions of blindness globally.
The only conventional treatment is steroid therapy,
which has serious side effects and cannot be used long-term.

fungal feet rising with free-diet elderly

5.14: news.health/
heavy skin or nail growth can be fungal infection:
Dr. Leonard Vekkos, a podiatrist
toenails seem to thicken as we get older?
The most common issue is the development of a fungus infection
called onychomycosis.
. diabetes or other medical conditions
create an immuno-compromised state
or a decreased circulation to the toenails .
Q. what fungus treatments are available?
A. The thickness caused by fungus can cause skin infections
that can lead to serious problems.
In general, many fungal infections can be treated by
debridement (trimming and cleaning) in order to relieve discomfort.

news.health/foot care to avoid fungal infection:
Here are 4 simple, yet powerful, tips to keep in mind:
    Don’t share your nail file [need Dog Nail Clippers?]
    Wear the right shoe size [Fergie Captive Women's Boots]
    Don’t go barefoot [Perimeter GTX Boots]
    Hydrate your cuticles with oils, like oil of oregano

retroviral AIDS for cats (FIV)

5.11: news.health/retroviral AIDS for cats (FIV):

feline acquired immune deficiency syndrome (FAIDS)

. the infected cat's saliva enters the other cat's bloodstream.
. endemic in some large wild cats, such as African lions.
Unlike domestic cats, these species do not necessarily
exhibit symptoms, perhaps because
they have developed evolutionary mutations
that confer resistance.

casual transmission:

It has never been established in HIV research
that an intermediate host, such as a mosquito or flea,
can transmit productive infection [Webb],
and the same is believed to be the case with FIV.
...
. bloodborne HIV in a syringe
can survive outside the human body
for periods up to several weeks;
viability is “influenced by virus titre,
volume of blood, ambient temperature,
exposure to sunlight and humidity” [Thompson].
While cause for concern among human drug users,
this is of little practical relevance to felines,
although the variables cited undoubtedly play some role in
an exposed environment as they do in a hypodermic syringe.
FIV, like HIV, is not particularly sensitive to
ordinary room temperature,
but is very sensitive to such variables as
pH level [AIDSMap],
a fact which accounts, for instance,
for inactivation by stomach acid.
...
Blood, of course, contains {FIV, HIV} viruses
and can be shed.
Drying does not seem to affect the infectivity of HIV,
and the same is probably true of FIV [AIDSMap].

mosquitoes not a problem (whew!):

. it is not possible to get HIV from mosquitoes.
When taking blood, mosquitoes do not inject blood
from any previous person.
The only thing that a mosquito injects is saliva,
which acts as a lubricant
and enables it to feed more efficiently.

raw egg virus might cause cancer

5.11: news.health/raw egg virus might cause cancer:
Michael Greger, M.D.:

the risk for cancers of the blood and bone marrow,
such as non-Hodgkins lymphoma, various leukemias,
and myeloma (more details in my 2 min. video
EPIC Findings on Lymphoma).
Chicken consumption appeared the most hazardous,
associated with up to triple the cancer rates
for every 50 grams of daily poultry consumption
—that’s just a quarter of a chicken breast worth!
Why was there so much more lymphoma and leukemia risk
among those eating just a small serving of chicken a day?
As detailed in my 2 min. video
Chicken Dioxins, Viruses, or Antibiotics?,
the association between poultry and cancer
may be explained by the presence of
drugs, industrial carcinogens such as dioxins,
and/or the presence of oncogenic (cancer-causing) viruses.
In Poultry and [human] Cancer
I present the largest study to date
on poultry workers and cancer mortality,
which found a whopping 8-fold increased risk of
dying from penile cancer compared to controls,
a finding thought due to chicken virus exposure,
raising broader food safety concerns.
If chickens can be infected with
viruses linked to cancer in consumers,
then what about eggs?

These cancer-causing viruses found in chicken and eggs
are utterly destroyed by proper cooking,
so the primary risk of infection
would presumably be associated with
cross-contamination,
such as when mixing cake batter,
handling raw poultry, or even just
touching meat or shopping carts .

-- #oops that's my #raw #egg #diet, falling on my face!
6.5: yea but
you're already cancer-fried by touching shopping carts?!
don't forget your high-dose selenium!
and your hormonic(low-insulin), low-glycemic diet!!

calcium supp's cause arterial calcifications?

5.9: web,mis.health/
when do calcium supps cause arterial calcifications?:

. I had erroneously assumed that the
routine finding of arterial calcification in elders
was being made worse by the advice
to take calcium to fight bone resorption .

. calcification is a problem,
but in the calcium deficient test animal,
calcium-supp'ing, reduced calcification by 62%;
because,
when there's a deficit of calcium in the blood,
 the body excessively releases bone calcium
[20. Sanders S, Debuse M. 2003:89-90.]
and saturates soft tissues with calcium .

. so, could there be a bell curve effect,
where a deficit of calcium does
 flood the system with bone calcium,
but likewise, if you're taking megadoses of calcium,
that would have the same effect as low calcium?

. in any case, there is a study showing that
calcium supp's do increase the risk
of heart attacks by 27%;
and, lef.org points out the study's special conditions:
the risk from calcium is eliminated by
combining the calcium with sufficient levels of
calcium controlers (vit'd, vit'k, magnesium).
. not only does vit'k keep calcium in bones,
it has some way of keeping it off arterial walls,
[5.10: likely by making it latch onto more useful things,
that happen to be closer by .]

5.10: depends on form:
. certain forms of vitamin D are provoking bone resorption:
25-hydroxycholecalciferol
vs 1,25-dihydroxycholecalciferol
In 10 patients taking oral 0.25 micrograms of
1,25-dihydroxycholecalciferol twice daily for 7 d,
--[ Rocaltrol Oral Suspension (calcitriol) Rx ]--
calcium absorption increased more than in 10 patients taking
oral 40 micrograms of
25-hydroxycholecalciferol once daily for 7 d (p less than 0.02)
--[ the common D3 found in most supplements ]--
despite both groups having a
similar increase in plasma 1,25-(OH)2D.
These results support the view that the major effects of
oral 1,25-dihydroxycholecalciferol on absorption
is due to a local action on the gut
and that it is possible to increase
calcium absorption in osteoporosis
with oral 1,25-dihydroxycholecalciferol
without increasing its undesirable action on bone resorption.

6.5: may depend on dosing too:
. the form provoking the bone resorption
is also the most common form by far;
so maybe it would still be safer if
the dose was divided and taken with calcium ?
but too much calcium
inhibits conversion to the active form:

The following inhibit the activity of 1-hydroxylase enzyme
needed for making active vitamin D (calcitriol):
    # low parathyroid hormone (PTH)
     - PTH stimulates 1-hydroxylase.
     [see how common low PTH is, and what to do about it]
    # High calcium levels cause lowered PTH .
    # High phosphorus intake/high blood phosphorus.
    (An aside: Fructose we eat gets phosphorylated,
    grabbing phosphorus and holding it in the liver.
    So fructose (fruit) consumption can counter
    high phosphorus intake(dairy, fish, meat, soda) .)
    [don't mix high fructose with high-glycemic diet]
    # High concentrations of calcitriol
    - A negative feedback mechanism is in play, meaning,
    the more active vitamin D you have circulating,
the less active the enzyme.

. the Active vitamin D, also called calcitriol,
is a high-energy, twice-hydroxylated compound
with a very short half-life (about 5 hours)
- such that levels of active vitamin D are tightly controlled .
Serum concentrations of active vitamin D (calcitriol)
are not typically correlated with vitamin D intake,
or vitamin D stored as 25(OH)D3.
It is primarily calcitriol that is responsible for the
benefits we're discovering about this vitamin,
e.g. mineral balance and bone mineralization,
immunity, blood pressure control,
reduction in cancer cell proliferation, and insulin secretion.

list of calcitriol suppliers .
(CAS NO.     32222-06-3; 125338-24-1)

sports training for babies

5.12: web.care/sports training for babies:
. headline had me curious; but,
wasn't much of a story here except that
business was excited about feeding on new ways
that you could micromanage your kid ever-earlier
to help your kid get into an elite college .
. those who sell sports training for babies
got into trouble saying they make a difference,
so they don't say that any more,
but I was reminded of Tiger Woods:
how would you find out that guy is a natural at golf
unless you started him at age 4 ?
. some training I had in mind for literal babies
would be interaction that
kept their eyes following you;
for exercise, there is massage
and getting them to pull
with their reflexive grasping:
they will hold your fingers
and you can partially lift them this way .
www.nytimes.com/2010/12/01/sports/01babies.html
www.babiestoday.info/baby-development-stages
...sports-training..for-babies
www.momsteam.com/organized-sports-toddlers
-dont-give-them-edge-parents-are-promised

stamps.com (sent by mark levin radio)

5.17: proj.bus/mail/stamps.com (sent by mark levin radio):
summary:
"( . and the first thing you should do is click on the radio icon
and tell'em mark sent you . )
. but they act as if you know what you're signing up for;
in fact I had no idea until they asked for my credit card,
and found this cheap way to do stamps from home
is suitable only for businesses who do mass mailings,
because the service is $16 per month
-- heck, I haven't used that much postage in 10 years!

whole house surge protector

5.5: web.apt`gear/whole house surge protector:

summary:
. the best way to protect from lightning is to
get off the grid, and then to protect your own system,
use a lot of lightning rods at all the high points .