bone and muscle boosters

 2022.8.22: health/diet/osteo/hormonics/
bone and muscle boosters:

. one of the best things you can do for bones

is getting vitamin k2 to keep the calcium 

from being pulled out of bones by vitamin D.

Vitamin K2 doses need to much higher than vitamin K1 doses,

and I found only one supplement that provides a dose

proven effective in studies:

Life Extension Mega Vitamin k2, 45,000 micrograms of the mk4 form of K2.

https://www.lifeextension.com/vitamins-supplements/item02417/mega-vitamin-k2-high-potency-for-strong-bones

use of a bisphosphonate Fosamax (alendronate sodium) vs vitamin k2 (mk-4)

2022.4.6: health/diet/vit'k2/med/osteo/

use of a bisphosphonate Fosamax (alendronate sodium) vs vitamin k2 (mk-4):

summary:

. some studies show that the bisphosphonate 

Fosamax (alendronate sodium)

is not really helpful,and risks might include 

atrial fibrillation, but the evidence is conflicting.

. meanwhile, a study of vitamin k2 (mk-4)

was so effective it was hard to believe!

chronic illness increased after oils of soy, grain, and seeds added to diet

 2022.3.9: health/diet/omega-6/

chronic illness increased after oils of soy, grain, and seeds added to diet:

Dr. Chris Knobbe warns us that we are wrong about

omega-6 oil being healthy at higher doses.

AncestryFoundation 2021

https://www.youtube.com/watch?v=sKR1ZdHXXzo

Omega-6 Apocalypse 2 (AHS21)

Catherine Shanahan M.D. 2018: [ad]

http://www.amazon.com/dp/B01G1J7WEU/ref=nosim?tag=americiu-20

Deep Nutrition: Why Your Genes Need Traditional Food. 

#CBD slows #bone remodeling in study of #osteoporosis

19.12.17: news.health/osteo/cbd/
GPR55 antagonist reduced mouse bone resorption:
12.23: summary:
. bone strength is maintained by remodeling,
where bone is removed by osteoclasts
to make way for new bone by osteoblasts.
. CBD appears to inhibit osteoclast function
and might be of use against osteoporosis;
but it also increases the number of osteoclasts,
so that if you ran out of CBD for a time,
the osteoclasts would be reactivated,
and there would be many more of them.
. as seen with the Bisphosphonates
the strategy of stopping resorption is flawed,
and should rarely be used [Dr.Ott]
because while the bone may remain dense,
the bone is not maintaining its strength.

. interestingly, this is another situation
where CBD and THC counteract each other.

. as a strategy to control bone loss,
a person's hormone function is key;
[J Osteoporos. 2010]
but, never take hormones orally,
or when modified in some patented way;
that is how Hormone Replacement Therapy
got a bad reputation.
. see Dr.Lee about progesterone cream
for bone health as summarized by Dr.Jo.

can you trust Consumer Reports with vitamin D advice?

3.19: mag.health/diet/vit'd/
can you trust Consumer Reports with vitamin D advice?:
Consumer Reports [cr] on Health april 2019:
"do you really need more vitamin D?" [vd]
. new study with 2k IU for 5 years
didn't reduce risk of cancer or heart disease;
1600 IU in elders didn't prevent falls or build bone.
. this article implies that these are good studies
and that all prior studies showing benefits from vd supps
are all bogus or defective;
but this article has done nothing to prove that.
. if all the studies are good
it could mean that vd alone doesn't help;
you need other dietary and lifestyle changes too.

marine-sourced Hydrolyzed Collagen

4.11: 4.12: co.yt,web.health/diet/
Hydrolyzed Collagen/Dr.Rhonda Patrick:
Dr.Patrick, in her video:
. use a quarter cup of Hydrolyzed Collagen
(in a smoothie that may be divided into several meals);
2 rounded Tbsp contains 12g; cup/4 contains 4 tbsp;
so she is using up to 24g of Collagen
(2.64g of glutamic acid).
. during times of low glucose,
proline is released from connective tissue
for alpha-ketoglutarate for mitochondria
to create ATP for energy.
--. this gave me an idea that using collagen
may help preserve bone and teeth.

. I have 2 concerns, excitotoxicity,
and sourcing from beef rather than fish.
. based on Dr.Patrick's review I'll be trying this
but I'll take it in many small doses
and be sourcing it from fish.

adrenal fatigue

2.1: news.health/hormonics/adrenal fatigue:
Chris Kresser`adrenal fatigue:
. adrenal fatigue means high cortisol;
recovering from adrenal fatigue requires more than
just taking supplements and making diet changes;
stress management may include "a qigong routine,
guided mindfulness-based stress reduction practice,
and guided meditation practice".
see the 14-day 4-part program at 14four.me:
(the 4 parts include moving like your ancestors,
reboot your diet, manage your stress,
and get restorative sleep).

Dr.Oz #arthritis cure like #GAPS #diet

2.23: web.med/arthritis/Dr.Oz arthritis cure like GAPS diet:
Dr.Oz`guest: Jacob Teitelbaum, MD:
The 6-Week Arthritis Cure:

Rule out and treat infections and food allergies,
which can aggravate arthritis.
I usually treat my rheumatoid arthritis patients
with the antibiotic doxycycline
as this has been shown to be helpful in several studies.
The question is whether it
acts as an anti-inflammatory on its own
or is killing an infection causing the arthritis.

Dr. Oz and Suzanna's JIA 2013.2.21:
. in this show Dr. Oz talks about
a cure for juvenile arthritis
that was reported by the nytimes 2013.02 .

calcium for oat phytate and stimulation #cook

11.16: web.aq.cook/calcium powder:
18: summary:
. I believe adding calcium to oats
might inactivate their phytic acid;
and in experimenting with calcium
I found that it can be stimulating,
and could reduce the need for caffeine;
so I looked for the kind of supplement
that would come in powder form,
for mixing with oats and water,
and not have too much lead .

female #testosterone after #menopause

4.23: web.health/hormonics/female testosterone after menopause:
summary:
. a woman's life extension program should include
maintenance of youthful testosterone levels .

FoldRight reversed #arthritis ?

23: news.health/arthritis/FoldRight reversed arthritis?:



Jarek (Califonia USA) August 11, 2013
( reviewing Durk Pearson & Sandy Shaw's
Life Enhancement`FoldRight )

I'm 59 and I've been taking FoldRight for about nine months
hoping to feel younger (okay, don't laugh).
Unexpectedly, after the first month
my osteoarthritis improved
in my hands, knees and hip joints.
Now, nine months later
I can even snap my fingers!
My knees and hips no longer hurt
and my muscles seem firmer.
... I take two teaspoons
mixed in water before each meal.

so, what's in FoldRight?:

carnitine saves bone when thyroid acts up

8.5: web.health/osteo/
carnitine saves bone when thyroid acts up
. high T4 and high TSH (thyroid stimulating hormone)
results in lower bone density .
. however it may not be the thyroid directly;
rather,
high thyroid causes high cortisol
and high cortisol causes osteoporosis .
. when hyper-thyroid women were given carnitine
they had better bone density;
and it's known that after carnitine usage,
thyroid hormones can't get to their target;
but some thought this link was not direct:
rather, they theorized that
because carnitine may also lower cortisol
it could be the cortisol reduction
that has carnitine saving bone .
... however, I couldn't find anything on
carnitine's lowering of cortisol,
except that at huge doses it can raise cortisol;
so, I'm theorizing that the reason for
carnitine helping bone mass,
is that it prevents high thyroid activity
and then normalizing thyroid also normalizes cortisol,
which then normalizes bone density .
. any hyperthyroid osteoporosis with normal cortisol?
. Thyroid hormone directly stimulates bone resorption
in organ culture .
. hyper-thyroidism is associated with
accelerated bone remodeling;
conversely,
hypo-thyroidism is associated with
bones that are denser but not stronger
suggesting a retarded resorption
(bone building adds the density
but matched breakdown is needed for strength).

calcium supp's cause arterial calcifications?

5.9: web,mis.health/
when do calcium supps cause arterial calcifications?:

. I had erroneously assumed that the
routine finding of arterial calcification in elders
was being made worse by the advice
to take calcium to fight bone resorption .

. calcification is a problem,
but in the calcium deficient test animal,
calcium-supp'ing, reduced calcification by 62%;
because,
when there's a deficit of calcium in the blood,
 the body excessively releases bone calcium
[20. Sanders S, Debuse M. 2003:89-90.]
and saturates soft tissues with calcium .

. so, could there be a bell curve effect,
where a deficit of calcium does
 flood the system with bone calcium,
but likewise, if you're taking megadoses of calcium,
that would have the same effect as low calcium?

. in any case, there is a study showing that
calcium supp's do increase the risk
of heart attacks by 27%;
and, lef.org points out the study's special conditions:
the risk from calcium is eliminated by
combining the calcium with sufficient levels of
calcium controlers (vit'd, vit'k, magnesium).
. not only does vit'k keep calcium in bones,
it has some way of keeping it off arterial walls,
[5.10: likely by making it latch onto more useful things,
that happen to be closer by .]

5.10: depends on form:
. certain forms of vitamin D are provoking bone resorption:
25-hydroxycholecalciferol
vs 1,25-dihydroxycholecalciferol
In 10 patients taking oral 0.25 micrograms of
1,25-dihydroxycholecalciferol twice daily for 7 d,
--[ Rocaltrol Oral Suspension (calcitriol) Rx ]--
calcium absorption increased more than in 10 patients taking
oral 40 micrograms of
25-hydroxycholecalciferol once daily for 7 d (p less than 0.02)
--[ the common D3 found in most supplements ]--
despite both groups having a
similar increase in plasma 1,25-(OH)2D.
These results support the view that the major effects of
oral 1,25-dihydroxycholecalciferol on absorption
is due to a local action on the gut
and that it is possible to increase
calcium absorption in osteoporosis
with oral 1,25-dihydroxycholecalciferol
without increasing its undesirable action on bone resorption.

6.5: may depend on dosing too:
. the form provoking the bone resorption
is also the most common form by far;
so maybe it would still be safer if
the dose was divided and taken with calcium ?
but too much calcium
inhibits conversion to the active form:

The following inhibit the activity of 1-hydroxylase enzyme
needed for making active vitamin D (calcitriol):
    # low parathyroid hormone (PTH)
     - PTH stimulates 1-hydroxylase.
     [see how common low PTH is, and what to do about it]
    # High calcium levels cause lowered PTH .
    # High phosphorus intake/high blood phosphorus.
    (An aside: Fructose we eat gets phosphorylated,
    grabbing phosphorus and holding it in the liver.
    So fructose (fruit) consumption can counter
    high phosphorus intake(dairy, fish, meat, soda) .)
    [don't mix high fructose with high-glycemic diet]
    # High concentrations of calcitriol
    - A negative feedback mechanism is in play, meaning,
    the more active vitamin D you have circulating,
the less active the enzyme.

. the Active vitamin D, also called calcitriol,
is a high-energy, twice-hydroxylated compound
with a very short half-life (about 5 hours)
- such that levels of active vitamin D are tightly controlled .
Serum concentrations of active vitamin D (calcitriol)
are not typically correlated with vitamin D intake,
or vitamin D stored as 25(OH)D3.
It is primarily calcitriol that is responsible for the
benefits we're discovering about this vitamin,
e.g. mineral balance and bone mineralization,
immunity, blood pressure control,
reduction in cancer cell proliferation, and insulin secretion.

list of calcitriol suppliers .
(CAS NO.     32222-06-3; 125338-24-1)

caveats to prunes preventing osteoporosis #health #osteo

4.5: health/prunes
5.3, 5.4: summary:
. prunes (dried plums) have a dramatic effect on bone growth,
primarily by  [my inference]
increasing parathyroid hormone (PTH)
but prunes also raise IGF-I (insulin-like growth factors)
which increases the risk of cancer .
. plums also have a special sugar, sorbitol,
that enhances calcium absorption
or increases bone metabolism;
but, plums also have a high infammatory index,
due to the sheer quantity of their total sugars;
the plum's sorbitol may reduce bone resorption,
but this is better done with xylitol .
. other ways dried plums can help bones
is their generous serving of boron and vitamin K; [5.9:
but again, there are better sources:
while boron is required by plums,
it seems likely that the prune's boron levels
would depend on how much is in the soil;
therefore, supplements would be a safer bet .
. by far the best sources of vitamin K
are the dark green leafies .]

. a better strategy for bone growth
is to make sure your diet is avoiding growth inhibitors:
bones need IGF sensitivity,
which in turn needs both load-bearing exercise
and proper insulin sensitivity (that entails
a low-glycemic, low-cortisol diet).

. cortisol is raised by low blood sugar
(the usual reason sugar gets low is when a diet has
too many simple sugars and grains,
and then the insulin response over-reacts
which swings sugar from too high to too low).
. cortisol is also caused by chronic stress, or lack of sleep .

. lowering cortisol is the most dramatic way to
increase insulin sensitivity,
which is critical to bone growth because,
if your cell's can't hear the insulin calling,
they are also deaf to the other growth factors
(also known as anabolics); these include
GH (growth hormone),
IGF (insulin-like growth hormone),
and PTH(parathyroid hormone).
. along with using a low-glycemic diet,
cortisol can be further lowered by supplements:
the combination of arginine and lysine .

. other ways to increase insulin sensitivity include
load-bearing exercise and supplements:
magnesium, alph lipoic acid, L-carnitine, taurine, L-arginine,
chromium, coenzyme Q10, silymarin, Inula racemosa ... .

. perhaps there could be safety by cycling the IGF?
the usual diet should be low-glycemic,
and include herbs that lower IGF;
but every couple days,
take your prunes before and after bone training
(weightlifting or squats, pushups, etc).]

. the usual form of vitamin D
promotes bone resorption,
which is good for healthy bone turn-over,
but the needed rebuilding after resorption
will only happen if one is not resistant to anabolics .

recovering from artificial joint surgery #med #osteo

bone will heal much faster if you
load up on vit'c and arginine;
I get mine cheap here: BeyondACenturyInc.

#thyroid optimization may save bone,vision #health

11.2 ..11.4: health/thyroid/
lifestyle choices that improve function:
summary:
low thyroid is very common:
. age-related hypo-thyroid
-- ie "(normal) TSH levels --
is as common as the many modern diseases,
and that may be more than a coincidence .
. there are ties to bone loss,
atrial fibrillation,
and blindness due to glaucoma
(you may be at increased risk if you are
nearsighted or hypo-thyroid).

. I will first explain how common low thyroid is,
and how it can be mistaken for hyper-thyroid
-- that's important to realize because
some are avoiding the iodine they need
under the assumption that they are hyper-thyroid
when, in fact,
both the low and high thyroid extremes
can have the same symptoms
of a rapid or erratic heart .

. the unprecedented rate of obesity starting in the 1980's
may be due to the combination of
not only replacing sugar with high-fructose corn syrup,
but also replacing the iodine in bakery goods
with bromides that actually inactivate
what little iodine you might already be getting !