mediterranean diet may benefit from mushrooms

17.12.3: 18.7.2: news.health/diet/
mediterranean diet may benefit from mushrooms:
Ergothioneine is a naturally occurring amino acid
and is a thiourea derivative of histidine,
containing a sulfur atom on the imidazole ring.
This compound is made in relatively few organisms,
notably Actinobacteria, Cyanobacteria, and certain fungi.
Food Chemistry, 2017;
Mushrooms: A rich source of the antioxidants
ergothioneine and glutathione.
prof Beelman:
(professor emeritus of food science and director of the
Penn State Center for Plant and Mushroom Products for Health)
. countries that have more ergothioneine in their diets,
like France and Italy,
also have lower incidents of neurodegenerative diseases,
like Parkinson's Disease and Alzheimer's.
-- about five button mushrooms each day.

Dr.Jay Sordean`outsmarting the #dementia epidemic #alz

6.3: bk.health/diet/alz/
Dr.Jay Sordean`outsmarting the dementia epidemic:
book review of Dr. Jay Sordean 2015`
Outsmarting the Dementia Epidemic:
7 Key Memory Care Actions to Avoid Alzheimer's
and Successfully Keep Your Brain Safe, Sharp
and Sexy Into the Future.
. his website pages related to this topic
and fb news feed.

curcumin for #parkinsons

7.21: news.med/parkinsons/curcumin:

. curcumin is found in turmeric spice;
curcumin can reduce the progress of Parkinson's
by inhibiting the misfolding and bunching up
of the brain cell protein alpha-synuclein.
. curcumin can reduce ROS (stressful oxygen radicals)
that are associated with Parkinson's.
. alpha-synuclein toxicity can cause apoptosis (cell suicide),
and curcumin can protect cells against that
[BMC Neurosci. 2010].

other things curcumin can do for the brain:
. Curcumin can chelate metals that cause
oxidative damage to lipids, proteins, and DNA.
. it can inhibit inflammation (stongly associated
with brain cell death in Parkinson's)
and, stimulate beneficial microglial phagocytosis
[immune cells in brain eat unwanted material]
to clear amyloid out of brain.

. removing amyloid might reduce the formation of
the α-synuclein amyloid fibrils found in Parkinson's;
because, the α-synuclein tends to form aggregates
when seeded by other aggregates (amyloids)
[J Biological Chemistry 2005].

. curcumin extracts are poorly absorbed;
perhaps the most potent curcumin formula
is Relentless Improvement's Curcumin
unless you're allergic to Polyvinyl pyrrolidone.

lucidamide for #parkinsons

7.19..22: news.med/parkinsons/lucidamide:
7.22: summary:
. noöpept (available as lucidamide)
has been shown in nerve cells in a dish
to save them from death due to the addition of
the alpha-synuclein that is associated with
cell damage in Parkinson's .
. while this alone hardly warrants use in humans,
noopept is known to be safe for humans,
and is used for enhanced memory and less anxiety.

chriskresser.com` #parkinson's disease

2.6: news.health/parkinson's disease/chriskresser.com:
. Chris Kresser, M.S., L.Ac talks about
new findings in the study of Parkinson’s disease .

link between alz and sugar may be cholesterol

4.13: news.health/alz/
 link between alz and sugar may be cholesterol:
4.13, 4.17: summary:
. when alzheimers was reported to be a clumping of protein
and related to diabetes,
I had assumed it was a glycation problem,
but here is evidence that cholesterol is implicated
by way of reducing leptin levels
which apparently is what prevents the formation of amyloid-β
and the occurrence of phosphorylated tau .
. the way it all ties together is that
cholesterol is elevated by sugary diet,
and a sugary diet is a leading cause of diabetes
(see the theory and results of an epi'study).