progesterone is equally a male hormone

20.5.12: health/hormonics/
progesterone is equally a male hormone:
wbur.org 2020:
"Doctors Test Whether Female Sex Hormones
Could Help Men Fight COVID-19"
[progesterone is an anti-inflammatory]
--
this news is promoting a common misconception!
progesterone is a female hormone? no!
. men's levels of progesterone are similar to
those of fertile women before month's ovulation.

John E. Whitcomb, M.D anti-aging

4.30: aq.med/John E. Whitcomb, M.D anti-aging:
5.4: summary:
. a friend using integrative medicine for cancer
(using both chemo and functional medicine)
introduced me to an anti-aging doctor
who has a blog I found very helpful
and who has a clinic in Brookfield, Wisconsin
with BHRT (bioidentical hormone replacement therapy)
probiotics, and anti-aging diet management .
. I briefly explore his blog's advice,
and give a summary of his LiveLongMD.com site .

bio-identical hormones attacked

5.8: news.pol/healthcare/bio-identical hormones attacked:
Action Alert! If you are a resident of
Alaska, Connecticut, Colorado, Georgia,
Illinois, Iowa, Kansas, Kentucky, Maryland,
Massachusetts, Minnesota, North Carolina,
Pennsylvania, Rhode Island, South Carolina,
Tennessee, Utah, Vermont, Washington,
Wisconsin, or Wyoming,
please contact your member of the Senate HELP Committee
and ask him or her to strike the extreme language in this bill
that has nothing whatsoever to do with safety.
Please take action immediately!

caveats to prunes preventing osteoporosis #health #osteo

4.5: health/prunes
5.3, 5.4: summary:
. prunes (dried plums) have a dramatic effect on bone growth,
primarily by  [my inference]
increasing parathyroid hormone (PTH)
but prunes also raise IGF-I (insulin-like growth factors)
which increases the risk of cancer .
. plums also have a special sugar, sorbitol,
that enhances calcium absorption
or increases bone metabolism;
but, plums also have a high infammatory index,
due to the sheer quantity of their total sugars;
the plum's sorbitol may reduce bone resorption,
but this is better done with xylitol .
. other ways dried plums can help bones
is their generous serving of boron and vitamin K; [5.9:
but again, there are better sources:
while boron is required by plums,
it seems likely that the prune's boron levels
would depend on how much is in the soil;
therefore, supplements would be a safer bet .
. by far the best sources of vitamin K
are the dark green leafies .]

. a better strategy for bone growth
is to make sure your diet is avoiding growth inhibitors:
bones need IGF sensitivity,
which in turn needs both load-bearing exercise
and proper insulin sensitivity (that entails
a low-glycemic, low-cortisol diet).

. cortisol is raised by low blood sugar
(the usual reason sugar gets low is when a diet has
too many simple sugars and grains,
and then the insulin response over-reacts
which swings sugar from too high to too low).
. cortisol is also caused by chronic stress, or lack of sleep .

. lowering cortisol is the most dramatic way to
increase insulin sensitivity,
which is critical to bone growth because,
if your cell's can't hear the insulin calling,
they are also deaf to the other growth factors
(also known as anabolics); these include
GH (growth hormone),
IGF (insulin-like growth hormone),
and PTH(parathyroid hormone).
. along with using a low-glycemic diet,
cortisol can be further lowered by supplements:
the combination of arginine and lysine .

. other ways to increase insulin sensitivity include
load-bearing exercise and supplements:
magnesium, alph lipoic acid, L-carnitine, taurine, L-arginine,
chromium, coenzyme Q10, silymarin, Inula racemosa ... .

. perhaps there could be safety by cycling the IGF?
the usual diet should be low-glycemic,
and include herbs that lower IGF;
but every couple days,
take your prunes before and after bone training
(weightlifting or squats, pushups, etc).]

. the usual form of vitamin D
promotes bone resorption,
which is good for healthy bone turn-over,
but the needed rebuilding after resorption
will only happen if one is not resistant to anabolics .

modulation of hormones with food and herbs #cancer #hormonics #BHRT

2.25: web.health/hormonics/anti-cancer
modulation of hormones with food and herbs:
[!] adapted from: 11.9.23:
news.health/hormonics/meridianvalleylab.com
intro:
. this explains how hormones of both men and women
can be affected by dietary changes .
. both men and women are often over-producing their
estrogen, cortisol, insulin,
and are thereby mismanaging their
progesterone, DHEA, and testosterone .
. this advice is mainly a paraphrasing of the
naturopathic doctor, Dr. Barry Wheeler,
who uses bio-identical hormone replacement therapy
while testing for current hormone levels
(see resources at bottom).

cancer prevention: estrogen quotient(EQ)

 EQ(should be > 1 ) =
            E3[estriol]
-----------------------------------------
(E1[estrone] + E2[estradiol])

. an iodine + iodide mix can induce a healthy EQ
by converting E1 to E3,
(16-alpha-hydroxy-estrone is a middle step)
. use 3...4 doses of {Iodoral, i-Throid}
or 6...8 drops of Lugol’s iodine (Rx).
[. an iodine-rich diet is yet another reason why
the Japanese are protected from breast cancer .]

DHEA is anti-cancer but beware oral use:
. low DHEA can increase the risk of cancer;
but oral DHEA is a common cause of high estrone (E1);
use it only transdermally [cream, inhaled] .

methyl-donors are anti-cancer agents:
. E1 and and esp'ly 4-hydroxy-E1
increase cancer risk.
. a diet that raises 2-methoxy-E2
can usually lower 4-hydroxy-E1 levels .
. this is done with methyl-donors:
# the methylcobalamin form of vitamin B12,
# the methylfolate form of folate/folic acid,
# S-adenosylmethionine (SAMe),
# betaine, and glutathione.

The 2/16 ratio:

. conversion of E1 to the good E3
is done by first producing the pro-cancer
16-alpha-hydroxy-estrone;
and then converting that to anti-cancer E3 .
. things that reduce 16-alpha-hydroxy-estrone
will tend to raise 2-hydroxy-estrone .

. the Brassica family can shift 2/16 ratio:
(Broccoli, cauliflower, cabbage, Brussels sprouts,
bok choy, mustard greens, and kale)
. the active ingredient is indole-3-carbinol (I3C)
and di-indolylmethane (DIM);
but, if using a veg'concentrate, beware overdose:
they can stop E1 from being converted to the E3
that is needed to maintain a healthy EQ
and avoid osteoporosis .
. men who eat Brassica vegetables four times a week
have 40 % less risk of prostate cancer .

Other supplements for 2/16 ratio:
magnesium (300 milligrams daily),
vitamin B6 (50 milligrams a day)[beware nerve damage]
vitamin E (600 IU at bedtime)[beware flu eroding heart]

paths for making testosterone:

. not only is testosterone decreasing in elder men,
but estrogens may increase by up to 40% .
. aromatase converts T to estradiol,
while 5AR (5-alpha-reductase) converts T to
DHT (5α-dihydro-testosterone).

. the 5AR is also doing other conversions as well:
# Androstenedione -> andosterone
# Cortisol -> allo-tetrahydro-cortisol .
. DHEA up-regulates 5AR activity
[ ... perhaps this how it balances cortisol,
by reducing it to allo-tetrahydro-cortisol ?]

Progesterone inhibits 5AR .
[. often thought of as a woman's hormone,
progesterone is the man's primary device for
preserving testosterone! ]

convert DHT to anti-cancer hormones:

. it's a myth that DHT needs to be suppressed;
while an over-abundance of DHT can be a sign of
estrogen's dominance over progesterone,
the other key to avoiding prostate cancer may be found in
converting any DHT to the anti-cancer androgens:

# androstanediol, [(5α-androstane-3α,17β-diol)
-- also known as 3α-diol (3α-Androstanediol)  --
is catalyzed by the enzyme 3-α-HSD .]
[. 3α-diol can be potent:
it can provide a key signal for progression of
androgen-independent prostate cancer .

# 3β-Adiol  (5-alpha-androstane-3-beta-17-beta-diol).
[3β-Androstanediol catalyzed by the enzyme 3-β-HSD .]
. 3β-adiol is inhibited by some Heavy metals,
such as cadmium and arsenic (prostate cancer risks).
. 3β-Adiol stimulates only estrogen receptor beta,
and has anti-proliferative and re-differentiation activities;
it also modulates the brain's stress response .

 . beware powerful anti-DHT prescriptions
-- the 5-alpha reductase inhibitors --
because they are also lowering androsterone[s] .
. Saw palmetto can lower 3β-Adiol too much .

. the best way to control DHT production
is by maintaining progesterone function
(don't have too much estrogen).
. some food ingredients are 5-alpha reductase inhibitors:
    GLA (grass fed animals)
    EPA fish oils,
    Vitamin D3
    Zinc -- B6 can potentiate this .

testosterone's aromatization to estrogen:

. ways men make estrogen:
# androstenedione -> testosterone -> estradiol
# androstenedione -> estrone .
. chronic high insulin is the main cause of
men's testosterone being aromatized into estrogens;
however, a low-insulin diet is not a quick fix:
it could take 2 years to normalize aromatization .

. herbal ways to reduce aromatization include
Myomin (a combination of Chinese botanicals)
and chrysin liposomal spray ).
[. I could not find any liposomal versions of chrysin ...]

[Dr Chi's Myomin:
Myomin contains Aralia, and Cyperus rotundus;
both reduce estradiol [volume and function]:
by inhibiting the aromatase enzyme,
and preventing estradiol from binding to receptors.
. Myomin also contains Smilax glabra, [anti-diabetic]
and Curcurma zedoria .
. Myomin may raise levels of interferon (IFN)
to stimulate natural killer cells,
and raise interleukin-2 (IL-2)
to induce the proliferation of immune cells .]
[ Curcurma zedoria(White Turmeric):
Chang Minyi` AntiCancer Medical Herbs
(Hunan Science and Technology Publishing House, 1992):
Curcuma zedoaria ... breaks ribosoma formation in cancer cells, ... .
.... possibly related to
RIP (Ribosome inactivating protein) function .]

resources:

# Dr. Barry Wheeler's hormone balancing articles .
# Bio-Identical Hormone Replacement (BRHT):
risks you should know and how to reduce them
# BHRT is not easy after HRT proven wrong
# other Nutrition & Healing articles
# Bioidentical hormone Physician referrals:
American College for the Advancement in Medicine
or the American Academy of Environmental Medicine .
# Wright`Taking The Fear Out of
Bio-Identical Hormone Replacement Therapy
- One Urine Test at a Time
# more about chinese herbs .