#caffeine causes liver to release glucose

12.19: web.cook/caffeine/causes liver to release glucose:
. caffeine makes your liver release sugar;
also, you can feel the brain sugar increasing
and it may come from raising cortisol
which causes insulin resistance in muscles
so they are less able to use blood sugar
thus leaving more for the brain .
. people running low on carbs still need brain glucose,
and they get it from the liver
which converts fat into sugar .
. something about caffeine is moving hormones
which in turn pulls more sugar from liver .
web:
"the caffeine-induced increase in sympathetic activity
may stimulate endogenous glucose production" [PMC1464218];
"Caffeine ingestion has been demonstrated to
increase circulating epinephrine and norepinephrine" [8964766];
"epinephrine is a potent stimulator of gluconeogenesis
in humans" [PMC1464218].
. therefore, caffeine very likely does promote
gluconeogenesis (liver's release of glucose) in humans .

glycerine sweet relief from dry skin on hands

5: co.iherb/cook/glycerine/sweet relief from dry skin on hands:
. after I started using too much caffeine,
it raised my cortisol and lowered my dhea,
which then made me unable to sweat
so my fingers felt so dry it was annoying;
but, glycerine keeps the moisture on your hands
without making them feel greasy .
. this is the same stuff as in Sortkwik
meant to help paper handlers get a better grip .
. it washes off with hand-washing,
so I keep some in a little squeeze bottle
in my pocket at all times . [8:
( I mix 1 part water to 3 or 4 parts glycerine ).]

#caffeine increased microvascular flow by 30%

11.22: news.health/caf/increased microvascular flow by 30%:
Masato Tsutsui, MD, PhD:

. Previous studies have revealed improvement in
large artery function in association with
caffeine consumption,
as well as a reduced risk of dying from
cardiovascular disease.
. a double-blind crossover study showed that
caffeine contained in a cup of coffee
improves microvascular endothelial function
in healthy individuals
(that is a measure of vascular resistance
within microvessels and tissue blood flow).
. five ounce cup of coffee with caffeine
was compared to decaf
to evaluate microscopic blood circulation.
(Blood flow to the fingers is an indicator of
small blood vessel endothelial function.)
. the caffeine increased blood flow by 30%
in comparison with those that received the decaf
over a 75 minute period .

12.24:
. I often use caffeine pills for relief from
heart ache due to blood vessel constriction;
but recently I've had chronic inflammation issues
due to autoimmune or infection
and coincident with that an edema indicating
poor endothelial function;
and high-dose caffeine has not cured this .

link between alz and sugar may be cholesterol

4.13: news.health/alz/
 link between alz and sugar may be cholesterol:
4.13, 4.17: summary:
. when alzheimers was reported to be a clumping of protein
and related to diabetes,
I had assumed it was a glycation problem,
but here is evidence that cholesterol is implicated
by way of reducing leptin levels
which apparently is what prevents the formation of amyloid-β
and the occurrence of phosphorylated tau .
. the way it all ties together is that
cholesterol is elevated by sugary diet,
and a sugary diet is a leading cause of diabetes
(see the theory and results of an epi'study).