21.7.12: web.health/diet/
Cares Act 2020 required removing guaifenesin from asthma meds:
. why was primatene recalled?
a competitor claimed that the Cares Act 2020
required removing guaifenesin;
possibly due to it being known that
guaifenesin may cause birth defects.
but that was known at least as far back as 2003.
[ Am Fam Physician. 2003:
https://pubmed.ncbi.nlm.nih.gov/12825840/
Over-the-counter medications in pregnancy
Ronald A Black, D Ashley Hill.
https://www.aafp.org/afp/2003/0615/p2517.html
]
bronkaid`inactive ingredients:
https://bronkaid.com/
*dibasic calcium phosphate *dihydrate,
magnesium stearate, microcrystalline cellulose, polyethylene glycol,
*polyvinyl alcohol, silicon dioxide, sodium starch glycolate,
stearic acid, talc.
With the passage of the Cares Act in 2020
the makers of Bronkaid were required to
reformulate the product to remove guaifenesin.
The new formulation, called Bronkaid® Max,
still contains the bronchodilator Ephedrine Sulfate.
. the same thing happened to primatene tablets.
Dr.rajivdesai:
https://drrajivdesaimd.com/2021/03/16/over-the-counter-otc-drugs/
. during pregnancy, Guaifenesin has been associated with
an increased risk of neural tube defects.
Table below summarizes safety of Over-the-Counter
Antihistamines, Decongestants, and Expectorants in Pregnancy:
Guaifenesin
Expectorant
Pregnancy risk category C
Safety not established, should be avoided in first trimester.
. Multiple herbals, such as mugwort, blue cohosh, black cohosh,
goldenseal, juniper berry, chaste berry, rue, and pennyroyal oil,
are uterine stimulants or abortifacients
and should be avoided in pregnancy.
Although ephedra is commonly used during pregnancy
according to patient report,
it has a significant association with birth defects.
According to the NBDPS,
ephedra is associated with anencephaly (OR = 2.8).
Other weight loss products, with or without ephedra,
are associated with dextro-transposition of the great vessels
and aortic stenosis.
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