2021-05-18

high fat vs high carb diet improves omega-3 vs 6 ratio?

 21.2.19: co.reddit/news.health/diet/omega-3/
high fat vs high carb diet improves omega-3 vs 6 ratio?:

. even when the diet's omega-6/omega-3 ratios are nearly the same,

the High fat diet group had a lower omega-6/omega-3 ratio

than the High carb diet group. 


Metab Syndr Relat Disord. 2021 

https://pubmed.ncbi.nlm.nih.gov/33570478/

A High-Fat Diet Induces Lower Systemic Inflammation

than a High-Carbohydrate Diet in Mice.

. compared to the high carb diet,

The High Fat Diet group had lower (P < 0.05) ratios of

n-6 PUFA:n-3 PUFA, 

palmitic acid:ALA, 

myristic acid:DHA,

and lower plasma levels of proinflammatory cytokines

(IFN-γ, MIG, GM-CSF, and IL-6). 

Conclusion: The HFD mice showed lower systemic inflammation 

compared with a caloric ingestion-body weight-matched control HCD mice.

Background: 

a high-fat diet (HFD) 

high-carbohydrate diet (HCD). 

HFD mice exhibit a lower inflammatory state than an HCD

in the liver, skeletal muscle, and brain. 

In addition, we demonstrated that HFD and HCD 

modulated fatty acids (FA) composition in these tissues. 

In this study, our objective was to 

compare HFD mice and HCD mice in terms of

systemic inflammation. 

comments:

https://www.reddit.com/r/ScientificNutrition/comments/lm3oj3/a_highfat_diet_induces_lower_systemic/

> What kind of feed was used for the both groups?

[–]stranglethebars 5 points 1 day ago 

I'd also like to know that. I didn't see anything about it in the abstract. 

I would be surprised if they used high-quality fats and low-quality carbohydrates, though.

me:

https://www.reddit.com/r/ScientificNutrition/comments/lm3oj3/a_highfat_diet_induces_lower_systemic/gnt757f/

abstract says:

. compared to the high carb diet,

The High Fat Diet group had lower (P < 0.05) ratios of

n-6 PUFA:n-3 PUFA.

-- did that reflect the diet's ratios?

they say it reflects inflammatory process levels.

...

. here is a similar result where the diet is shown:

Nutrients. 2016

https://pubmed.ncbi.nlm.nih.gov/27801862/

Liver Fatty Acid Composition and Inflammation 

in Mice Fed with High-Carbohydrate Diet or High-Fat Diet.

Livers from the HFD group showed higher elongase activity, 

stored more polyunsaturated fatty acids (PUFAs) 

and had a lower omega-6/omega-3 fatty acid (n-6/n-3) ratio. 

dietary differences in omega oils:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133070/

Linoleic Acid (18:2n-6) omega-6

HCD: 1155.9 ± 9.7

HFD: 6653.5 ± 38.7 *

α-Linolenic Acid (18:3n-3) short-chain omega-3

HCD: 76.8 ± 0.5

HFD: 403.5 ± 19.2

Total omega-6 PUFA/ omega-3 PUFA ratio

HCD: 1155.9 ± 9.7 /76.8 ± 0.5 ~ 1156/77 = 15.0

HFD: 6653.5 ± 38.7 / 403.47 ± 19.2 * ~ 6653/403 = 16.5

. so even when the omega ratios are nearly the same,

the HFD group had a lower omega-6/omega-3 ratio. 


The Mediterranean Zone: Unleash the Power of the World's Healthiest Diet for Superior Weight Loss, Health, and Longevity Hardcover – 2014 by Dr. Barry Sears (Author)

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