interpreting JC's beatitudes

5.20: web.relig/jc/the beatitudes:

Jesus began to preach a message of repentance
because the kingdom of heaven was near (4:12-17).
In order to reach a wider audience,
He moved from Nazareth to the city of Capernaum,
on the shores of the Sea of Galilee,
but more importantly,
on the main highway through the land.
His declaration of beatitudes would come,
but not until He called for repentance.

google-plus's "(just the right people)

5.28: pos.cyb/net.g'+/blocked/
stay popular to prevent thread erosion:
. if you get blocked from anyone,
you can't see them on
any threads they participate in,
so then this has the effect of
blocking your view of other posts,
because they expect you can see
who they're responding to:
. so keep remembering,
g'+ is not the place for free speech;
it's the place to listen, and learn!
. you'll need to walk softly,
and carry your big stick elsewhere,
or on a dual g'+ account (haven't tried that yet). 

5.26: mis.cyb/net.g'+/being blocked 
hides posts in threads you can still see:
. while googling for g'plus news,
searching for myself on plus.topsy.com,
I found some comments directed at me
that g'plus didn't inform me of? :

recovering from brain atrophy

5.14: co.lef.org/med/apm/recovering from brain atrophy:
G Satyanarayanan

Can cognitive problems caused by
antipsychotic like risperidone
(ADHD, slow processing speed, low working memory)
and lithium(dyslexia, restlessness,
immediate and long term memory loss)
be reversed?
I was taking these medications for 4 years.
Now I 've stopped them
still now side-effects of those drugs not gone
so that I can say I have become normal
wrt those cognitive parameters.
Is cognitive problems caused by antipsychotic
like risperidone and lithium reversible?
What duration of such medications
beyond which such side effects
are not reversible- 2/4/6 years?

Ad: "Stainless Steel Meat Hammer"
me:
. Satyanarayanan asks about brain repair
after being on long-term anti-psychotics .
. these medications work by inhibiting dopamine function,
and atrophying the brain cells that make dopamine .
. the key is to find dopamine enhancers,
and anything that "(exacerbates schizophrenia)
and then anything that promotes neurite growth .
. I'm combining mct, blueberry extract,
and LE fishoil with DMAE for neurite growth .
. yohimbine extract promotes dopamine use,
and L-dopa (Mucuna Pruriens extract)
promotes dopamine production .
. you may have a lot of research ahead of you:
beware high blood pressure, etc .
. if I think of anything else for attention deficit,
I'll be putting them on my
performance enhancers list .

#antipsychotics are a total outrage

3.15: news.med/apm/antipsychotics are a total outrage:

Sandra G. Boodman washingtonpost.com 03-14-12:

Adriane Fugh-Berman, a physician, and associate professor
of pharmacology at Georgetown University,
was stunned by the question:
Two graduate students who had
no symptoms of mental illness
wondered if she thought they should take
a powerful schizophrenia drug
each had been prescribed to treat insomnia.
"It's a total outrage," said Fugh-Berman,
"These kids needed some basic sleep [advice],
like reducing their intake of caffeine and alcohol,
not a highly sedating drug."

. some of the public may not be aware
that physicians are not only outraged by
inappropriate use of psychiatric drugs,
but often also feel that the entire field of psychiatry
is "a total outrage" because they profess the very notion
that psychosis is a neurotransmitter imbalance
in need of a rebalancing medication .

. honest scientists will tell you something else:
emotions and chronic stress cause these imbalances;
and, the only reason for medications
is if your state doesn't have the money
to provide a secure environment for the mentally ill:
one that calms emotions, and reduces stress .

. remember that even when hallucinations exist,
they are no worse than reality;
both can be called the subject's environment,
and what makes mental illness dangerous
is not the hallucination,
but the policy of taking the law into one's own hands .
. what people are really afraid of from the mentally ill,
is the likelihood of responding to stress in an illegal way
because the mentally ill often believe in
pervasive conspiracies that would cause one to
lose faith in our legal system .

. the other problem that medications try to solve
is emotional contagion:
when people can't hold their emotions,
then those emotions get transmitted to others .

. finally there is the non-obvious problem:
what the psychiatrists are calling hallucinations
are really artifacts of supernatural disorders,
where people are exchanging thoughts silently
via devil-synchronized daydreams .
. this can cause great emotional distess,
as people have no way of controlling
what they {think, said} to others .
. these shared thoughts can be
esp'ly damaging in the workplace;
because, we have to be there -- and stay there --
for what seems like forever .
. if something evil is rubbing off on you,
it's got a lot of time to do that rubbing .
. if many are feeling you rub them the wrong way,
that's not a halucination,
and you may not even be mentally ill,
yet we should consider you to be socially challenged,
and there should be special programs for you,
that find an employment setting where you can fit in .

. if on the other hand, we chose to give you meds,
then you get diabetes, and raise our medicaid bills .
. capitalism can be efficient;
and christianity can be merciful;
but, when you try to mix them,
please don't think you get merciful efficiency .

. that would be a delusion,
unless it was religiously recognized ...
-- that gem can be found in the psychiatrist's dsm IV
(diagnostic and statistical manual).
. do you see what psychiatry is doing?
it's an army of politicians not scientists .
3.31:
. it doesn't matter that the "superstitious" might have
more insight or more proof
than conventional religious theories;
what matters is,
who is funding psychiatrists ? .
. psychiatrists had to stop calling
homosexuality a disorder,
and, in time, they will also have to stop calling
parapsychology a delusion .
. a belief in parapsychology is a key part
of the current schizophrenia diagnosis;
that's why they are called psychotic,
because they believe in what is
perfectly possible according to parapsychology .

iraq war ending, a real war is just beginning #ows #relig #pol #parenting

12.15: news.pol/purges/
iraq war is ending, and a real war is just beginning:

. NPR was asking the public how they felt
about the usa officially pulling out of iraq today .
. a marine who was one of the first to be
stationed at iraq's sea port, said,
"( what struck me about my job, is that
I had to replace some iraqi guy
who really did want to work
-- who wanted to care for his family ).

. no doubt that iraqi guy was already doing
a perfectly good job at defending that port!
(but the way the marine said it, at first made you assume
that usa hadn't had to take the port;
they just had to keep it secure,
and they could have just managed over the current crew,
but they didn't know how to trust them
(how do you care for your family, really,
when terrorists know you help the other side?))

. those guys wanted to work,
he poetically repeated in several places .
. wow, wasn't that the proverbial
"(your economy is just perfect now;
how do you feel? )!
--
. this call had at least 2 interesting surprises:
first I was reminded of #OccuppyWallStreet
who were said to be expecting a "(handout) for college;
because, here was a caller representing troops coming home;
and, you know, today's troops are often tomorrow's police
-- the same police having to face #ows protesters .
. then I was reminded that many marines
will be in similar job-hunting curcumstances
-- really wanting some sort of work
after they finish our war tour .
[. and not happy with just a handout .]

. well, trustables who want to work;
so, where will those jobs be?
. being trustworthy only works when you are
willing to pay people for what that trust is worth;
so, the jobs are going to people who
don't need to be trusted!
-- they're overseas, living in caves,
and can't possibly #OccupyWallStreet .

. the last idea from this call
came from the Carter admin':
at that time the military was angry with democrats
for telling the military to take a pay cut
(forgo inflation compensation)
yet the dem's still had plenty of fed money for what?
rolling out to welfare
-- for guys who didn't want to work,
and weren't conscerned about caring for their family .
[ie, the men were shadows to single welfare mom's .]

FUH-cake! psilocybin is almost respectable

6.17: web.wealth/psilocybin:

17/06/2011 (2000 GMT) bbc world service:
listen:
. the last segment (at minute:46) is
"(what makes mushrooms magic)
about a new study by Roland Griffiths, PhD,
contradicting doctrine by the war on drugs
(he shows psilocybin has therapeutic value).

. the newscaster, Julian Marshall,
was very angry at the end!
(it's barely audible in the replay version).
. well, he always sounds angry,
but he was actually cussing the researcher!
. this is a UK reporter;
and UK law had been strengthened in 2005
to make possession of even unprepared mushrooms
a schedule I offence .

. here is the end of the interview:
JM: think it should be legal for therapeatic uses?
Dr: that would be premature,
we're just know resuming experiments;
regulatory approval would need more scientific data backing it
JM: FUH-cake! (sounding quite like "(ache)
and a certain forbidden 4-letter word ).

. so what was that about?

Dr Griffiths' study in J.Neuropsychopharmacology
. at Johns Hopkins University School of Medicine
Dr. Griffiths, is Professor of Behavioral Biology,
Department of Psychiatry & Behavioral Sciences,
and, Professor of Neuroscience,
Department of Neuroscience .
. the study was partly funded by the
Council on Spiritual Practices .

Doses were based on body size and were 5 mg, 10 mg, 20 mg,
or 30 mg for every 154 pounds of body weight.
About 40% of study participants, or seven out of 18,
reported feeling extreme anxiety and fear
while they were on the two highest doses of the drug.
Six of the seven, however, experienced the fear while on
the highest dose of the drug.
Only one person reported negative fear effects on the 20 mg dose.
nearly 3/4 of people on the highest psilocybin doses
rated their experiences as mystical, transformative,
and highly beneficial.

graphic details at motherjones:
. 20mg per 70kg body weight was the
optimal dose for persisting positive mood
and increased well-being or life satisfaction .
. best working up from lesser doses
rather than starting with the target dose .

he did a similar study in 2006:

Johns Hopkins neuroscientist Roland Griffiths,
in a landmark 2006 experiment
published in Journal of Psychopharmacology
has 36 volunteers on 30mg psilocybin
who hadn’t previously taken the drug.
-- 30mg is [very]roughly equivalent to five grams
of dried psilocybe cubensis mushrooms .

. That study was the first in 40 years
to test a hallucinogen on people
in a clinical setting in the United States.
Formerly the focus of academic and government inquiry,
hallucinogens were abandoned by researchers
in the aftermath of the Sixties .

lib's for psilocybin info:
beckleyfoundation.org
drugwarfacts.org
council on spiritual practices
wiki
2008 psychiatric controls of shrooms

history of Psilocybin law:

The usa law that specifically banned psilocybin and psilocin
was enacted on October 24, 1968.
The latter substances were said to have "a high potential for abuse",
"no currently accepted medical use"
and "a lack of accepted safety".
On October 27, 1970, both psilocybin and psilocin
became classified as Schedule I
-- no known therapeutic benefit --
and were simultaneously labeled "hallucinogens"
under the “Comprehensive Drug Abuse Prevention and Control Act”
(section "Controlled Substances Act").
Most national drug laws have been amended to
reflect this convention
(see US Psychotropic Substances Act,
the UK Misuse of Drugs Act 1971,
and the Canadian Controlled Drugs and Substances Act),
with possession and use of psilocybin and psilocin
being prohibited under almost all circumstances,
and often carrying severe legal penalties.
[ in the UK you can get 7 years with the FUH-cakes .]
However,
in many national, state, and provincial drug laws,
there is a great deal of ambiguity about
the legal status of psilocybin mushrooms
and the spores of these mushrooms,
as well as a strong element of
selective enforcement in some places.
Additionally,
there has been a general shift in attitudes
regarding research with hallucinogenic agents .
. after a long moratorium,
many countries are revising their positions
and have started to approve studies to
test their physiological and therapeutic effects .

Magic mushrooms ban becomes law (2005)

. while dried mushrooms were illegal
fresh mushrooms were not;
The [UK] Drugs Act 2005 ends that loophole
and makes them a class A [usa`schedule I] drug

Exceptions will be made for people who
unknowingly pick the mushrooms in the wild
or find them growing in their garden,
and critics have argued
that the act will be difficult to police.

. use of the fungi has risen 40% in a year:
2002/03: 180,000
2003/04: 250,000
-- especially since the internet age,
and 400 "headshops" around the country.
. the vast majority of mushrooms sold [in 2005]
came from mushroom farms in Holland.
The law change does not affect
Fly Agaric (Amanita muscaria)
another, much more rarely used magic mushroom .

paddos in the netherlands

. risk assessment for paddos (mushrooms)
containing psilocin and psilocybin .
. the [Amsterdam] Coordination Centre
for the Assessment and Monitoring of new drugs .

. psilocybin and its metabolite psilocin
can be found in Psilocybe ssp.
Psilocybe semilanceata, Psilocybe cubensis,
Conocybe, Panaeolus and Inocybe, ...)
-- Psilocybe, is easily confused with
the highly nephrotoxic Cortinarius spp .

. of those under 24 who had tried it,
50% had done so only once or twice;
most youth are into socialable party drugs,
not religious experiences .
. regular users wait 3 weeks between doses
due to drug tolerance .

Amsterdam and the border regions
contain a relatively high number of
grow shops, and head shops,
in addition to smart shops,
esp'ly in the Red Light District .

. the sale of paddos makes up
50% of smart shops turnover.
--[ it appeared from their vague language
that this had to do with its being illegal;
ie, it was the shops themselves -- not the product --
that was turning over! ]

. biological variation of the active ingredient
is between 1% and 3.5% (usually higher in wilds,
and inactivated at temperatures above 50°C).
Usual dose is 1 gram of dried mushroom
= 10 grams of fresh mushrooms;
. approx. 6 – 12mg of psilocybin
is the typical hallucinogenic dose .
[6.18:
. according to the recent study, this might
simply be a safe starting dose for a batch
since the potency is so varied .]

. it causes an increase in serotonin in the brain
and a temporary reduction in
noradrenaline, dopamine and histamine.
. sideaffects:
. dilated pupils, loss of balance,
parestheses (pins and needles all over the body),
muscle relaxation, accelerated heartbeat,
dry mouth and nausea.
Psychological symptoms:
. many hallucinogenic compounds can cause
long-forgotten memories to resurface
and leave a deep impression on users.
[. the long-term psychiatric complaints
"(flashbacks, panic attacks)
are consistent with schiz'ia;
ie, the people who are smart eno' to
keep their schiz'ic delusions a secret
(involuntary thought broadcasting? loser!)
will complain only of flashbacks, panic,
anxiety or depression .]

Adrenergic blockers (such as neuroleptics and propanol)
generally act as imperfect antagonists.

6.17: the Silk Road
. speaking of room for shrooms,
here is an anonymous drug sales network:
http://ianxz6zefk72ulzz.onion/index.php
-- that's a TOR address;
the transactions are done in Bitcoins,
a potentially anonymous online currency .
To avoid seizures Silk Road recommends
using vacuum packing
and creative disguises to send goods.
6.18:
. one of the Bitcoin developers, Jeff Garzik, wrote:

"(Attempting major illicit transactions with bitcoin,
given existing statistical analysis techniques
is not very smart );

however,

there are methods of using Bitcoin in a fairly
anonymous manner .
not tying your Bitcoin address to any known alias that you use.
“washing” coins could be done via
many small transactions to various addresses
or by sending them through “laundering” services .
You could also have fresh coins
that you have “mined” yourself
which will not yet have a real trail
in the transaction log.

6.18: welcome to the underworld:

. after seeing the underworld links on tor

(ianxz6zefk72ulzz.onion - silk road (drugs)
627kx22vati6uqkw.onion
That's a guy who steals **** for you.
vms43o4cqysakvyb.onion - buy bitcoins via cash
am4wuhz3zifexz5u.onion
****-ton of books/other things to read.
Fo mah niggaz a bunch of PDF downloads on
building firearms and firearm training:
http://p2uekn2yfvlvpzbu.onion/
... )

at first I thought
all this anonymity makes it seem like
our law enforcement job is hopeless;
but did you see our computer security?
how could those guys be that dumb?
I suspect industry is in bed with the law:
deliberately creating security holes .

 

marijuana's role in schizophrenia

4.28: news.pol/medipot/pot's role in schizophrenia:
. pot before age 15 increases the risk of schiz'ia;
and, while there has not been an increase in schiz'ia
to match the increase in today's pot use,
there has likely been
no such increase in the teen world,
since the major cause of teen drug use
has nothing to do with policy!
. rather, it is a lack of teen supervision
and our inability to effectively fight a drug war
in an environment of privacy rights .
. pot increases dopamine,
and anti-schiz' drugs inhibit dopamine;
but the actual connection has to do with
a little-understood aspect of schiz'ia:
the major problem for the schiz'ic
is secretly breaking taboos
and then discovering the existence of
a spiritual world where there is no way
to hide secrets from telepathy .
. pot's increase of dopamine is both
hypersexualizing and disinhibiting,
making a youth more likely to
follow taboo impulses;
finally, the inevitable maturation process
(becoming aware of supernature)
means getting outed by telepathy
which then causes psychoses .
4.30:
. what I'm suggesting here is not that
every schiz'ic necessarily has
a problem with taboo secrets,
but with secrets in general;
ie, feeling too vulnerable from exposure,
(eg, others knowing you have no fighting skills
when you have very damaging opinions of others).

. anyone who doesn't admit the same
either hasn't matured, or
is not comfortable with
-- in any substantial way --
discussing the supernatural;
perhaps for the same reason
we have a history of burning witches,
so lets not even go there (?#!) .

america the beautiful mind

1.31:
. this is a story about a troubled genius
who was put on anti-schizophrenic med's
after being alarmed by radio jockeys
talking directly to him;
then, given no help without forced medication,
he eventually committed suicide .
. Dr. Breggin’s newest book, Medication Madness (2008),
describes dozens of cases of otherwise self-controlled people
who became spellbound by psychiatric drugs,
leading them to perpetrate bizarre acts,
including mayhem, murder and suicide .
. science has found evidence that failure to medicate
increases the risk of relapse;
but, what kind of relapse are we talking about here?
the public equates schizophrenia with violence;
whereas, schizophrenia puts people at risk for
bullying, mass rejection, and hopeless economic situations;
and it is the hopeless -- not the deluded --
who are doing the mass murders recently .

1.21: news.psy/schiz'ia/med's shoot another beautiful mind:
Orlando Sentinel `Darryl E. Owens 2008:
From very early on,
Dominic lived in his own shell.
for several weeks into day care,
he was silent .
[. he was said to have cursed a playmate to
give him back his "(damned whale)
-- perhaps the mother was actually referring to
the Bible's Jonah story?
. Jonah takes a ship ride to avoid god's plan
only to find god's storm coercing the shippers
to toss the escapee overboard
where god's whale was waiting to bring him back .
. schizophrenia, which challenged Dominic at age 29,
has a lot in common with Jonah's whale .

. schizophrenia is a sanctifier
(a way of setting one apart for god's use),
like so:
smooth socialization depends heavily on
not having a lot of real opinion sharing;
and, schiz'ics routinely broadcast their thoughts
which causes those nearby to mutter echoes of
such intrusive thoughts .
. assuming god makes thought transfer possible,
schiz'ia can thus be viewed as god`storms
that force others to distance themselves
from the one god is storming about .]

[with an IQ > "genius" + (SD15 or SD16)
(> 160 -- testing higher than 99.997%) ]
his smarts meant enrollment in gifted classes,
much to his chagrin.
"He had this sensitive feeling about equality"
his mother said.

As a child, Dominic preferred reading,
reveling in history and military affairs.
[yet], when he joined the Marines, [in the 90's]
his family was shocked.
[ the marines placed him into a prestigious
ceremonial unit stationed in Washington, D.C. ]

They figured he was just following his
older brother, Sebastian, a Navy SEAL.
[. a graduate of Oxford University
and the Navy's Basic Underwater
Demolition/SEAL (BUD/S) Class 195,

In 2003, Sebastian co-founded BCM,
a boutique private investment firm
that uses a proprietary algorithm
to exploit price trends in the major
commodity and financial futures markets
(and achieved an 80% return during the 2008 crisis).
Bastiat Blogger is a clearinghouse for
thoughts on hedge funds, global macro,
free markets, decision theory,
mixed-martial arts (MMA) and dueling culture,
private-sector tactical training, ...]

Dominic served six years,
earning his sergeant's stripes,
then left to pursue his passion: writing.
Still wanting to serve, [but as a non-leader?]
he joined the Florida Army National Guard.
He later enrolled at a Community College.
. in 2003-04, he served in Jordan and Iraq
working mostly security details with
Company C, 2nd Battalion, 124th Infantry Regiment .
--
[. an interpretation of why he left full-time then:

Sergeants serve as infantry squad leaders;
once a Marine reaches Sergeant,
their promotion no longer derives from a
composite or cutting score;
instead, they receive a Fitness Report.

. since schiz'ia was in his future (2003)
it's significant that he left just after
becoming a leader;
leadership is an stressful milestone;
and one reason for leaving at that point
could have been to intuitively avoid
an impending schiz'ic crisis;
it usually precedes a social role switch .
. perhaps there was less stress when blending in
and he didn't know just how paranormal
things would get during war's profanity .
1.31:
. another possibility is that he simply
needed to go part-time military in order to
start schooling .]

[. one of his most notable schiz'ic symptoms
was being convinced that voices on the radio
were talking to him directly.]

[. if there is a living god (or devil),
there's no reason why the deity can't
synchronize your life's specifics with the
random shoot-from-the-hip content of a radio jock .
. perhaps the supernatural was hinting:
"( why didn't a genius get a college degree first
and thereby get fast-tracked to a leadership role?
why aren't we using brains to do brain work
instead of gutter-balling gifts into the line of fire? ).]

[. seeing the details of Dominic's case,
I wondered if the supernatural mind was
being partial to his genius,
and tried using paranormal events to
convince him that death is more than chance:
in fact, war deaths often happen to
those who are special and try to pass as normal .]

Associated Press:
More than half of the suicides by veterans of
Iraq and Afghanistan returning 2001 ... 2005
were committed by members of the National Guard
or the reserves .

Sebastian:

. Army National Guard infantryman units
often suffer additional stresses
due to the fact that the soldiers' lives are
normally not specifically organized around
military deployments
(as an active-duty soldier's life would be);
such stresses may have promoted
schizophrenic thinking patterns:
Dominic was convinced that voices on the radio
were talking to him directly.
. Dominic would use his genius
to defend [paranormal] theories against
any attempts to establish that they were
incredibly unlikely, if not impossible.
. I was amazed at the intellectual acrobatics
and research efforts he would go to
to preserve a conspiracy theory
in the face of strong conflicting evidence .
. he saw things as overdetermined
and could not contend with the idea that
sheer randomness and coincidence
were major players in his world.

his father:

"We couldn't always understand what he was saying,
He was beginning to show signs of paranoia [schiz'ia]
and really thought [random] people
were trying to get him."

He was diagnosed with post-traumatic stress disorder,
prescribed [anti-psychotic?] medications,
and returned state-side several weeks ahead of his unit .

Sebastian:

. I know from personal experience
that as the anti-psychotic effects
reduced Dominic's paranoia symptoms,
they simultaneously caused his
quality of life to plummet
and his ability to concentrate
to fall off dramatically after a few weeks.
Unfortunately,
the tendency is to want the victim to
"get on with life" and find satisfaction in
work or school or relationships,
when in fact
the ability to do these things
is being attacked by the very medicine
that is used to treat the schizophrenia.

Dominic returned to school
but mostly stayed in the house.
Therapy and medication helped ...
his mother carried his pills up to his room .
--[. did she feel obliged to make sure
he took meds ?
perhaps he was having trouble finding employment
and could only get help from his parents
if he complied with psychiatry's genius-wilting chemo' ? .]

. shortly after [living at home on med's]
he slit his wrists,
[. a suicide attempt could cause a court-ordered
application of anti-psychotic medications:
danger to self for schiz'ic delusions
legally requires mind-wasting drugs
whose effectiveness as anti-aggression agents
is proportional to their destruction of
one's precious, life-embracing ability to write .]

. in the three months before [his successful attempt],
he'd tagged along on family trips to the
[GalM] -[apagos Islands] and Bermuda.
. a pistol exorcised the demons of Iraq 2004,
Dominic, 33, died on a monday,
[a week prior to saturday, September 20, 2008]

1.31: the PORT (Schizophrenia Patient Outcomes Research Team):
. PORT has been funded since 1992 by
the Agency for Health Care Policy and Research
and the National Institute of Mental Health
to develop and disseminate recommendations for
the treatment of schizophrenia
based on existing scientific evidence.

. maintenance doses below 300 mg CPZ equivalents per day
carry an increased risk of relapse,
although a substantial proportion of persons (up to 50%)
can be maintained successfully at these lower doses,
warranting a gradual and carefully monitored effort
to reduce dosage over time.

1.30: news.psy/schiz/meds/PORT updates:
PORT has updated treatment recommendations:
. the Schizophrenia Patient Outcomes Research Team (PORT)
has issued updated treatment recommendations .

. In contrast to efforts like the
American Psychiatric Association practice guidelines
and the Texas Medication Algorithm Project,
which attempt to address the full range
of situations clinicians encounter,
the PORT review authors limit their recommendations
to those interventions that have been tested in
randomized controlled trials.

. two large clinical trials have compared efficacy of
first- and second-generation antipsychotics:
the Clinical Antipsychotic Trials of
Intervention Effectiveness (CATIE)
and the Cost Utility of the Latest Antipsychotic Drugs
in Schizophrenia Study (CUtLASS).
For patients with chronic schizophrenia (1..2 years),
--[why limit at 2years? that was the study range]--
both first- and second-generation antipsychotics
are equally effective at preventing relapse;
however,
clozapine is an option for suicide risks .
[1.31: however, clozapine is hormonal murder .]

. selective serotonin reuptake inhibitors
are often prescribed for schizophrenic depression
yet have not been well studied in this population .

During maintenance therapy,
first-generation drugs may be used at
lower doses than those required to treat
the initial (acute) episode,
while second-generation drugs can be prescribed
at whatever dose was effective in the initial phase.

persistent auditory hallucinations
in spite of antipsychotic treatment
may respond to
low-frequency transcranial magnetic stimulation.
[$195 Sota Bio Tuner Pulser Bio Stimulator Massager Pulse BT7]

[repetitive TMS (Transcerebral Magnetic Stimulation):
< 1Hz reduces excitability
> 5Hz increases excitability .
. excitation before a task,
or for short bursts during a task
can enhance cognitive performance .]

. medication should be used in conjunction with
psychosocial interventions:

psychosocial # Assertive community treatment:
. a community-based multidisciplinary team,
low patient-to-staff ratios,
and frequent contact with patients.
Randomized controlled trials have consistently concluded
that this model reduces hospitalizations and homelessness,
when compared with standard care.
# The key element of supported employment programs is
# rapid job placement rather than an extensive training,
# integration of vocational and mental health services,
# solicitation of the patient's preferred job type
# support while on the job.

psychosocial # family therapy:
. when patients with schizophrenia have
ongoing contact with their families,
the relatives should be offered a family intervention (6...9 months).
Evidence suggests they help reduce rates of
relapse and rehospitalization for the patient,
and increase rates of adherence to treatment.

psychosocial # cbt:
. Cognitive behavioral therapy (4..9 months,
either in group or individual format)
can be helpful for med-resistent psychotic symptoms;
it involves a collaborative agreement about
symptoms to target in therapy
combined with the use of strategies
to improve the patient's ability to cope.

fig-leafing our responsibility to children

1.13: relig/bible/genesis/privatization of parenting:
[1.21: . capitalists and communists are still arguing about
whether privatization of production is an evil,
yet they are both still making a mess,
and they both agree on the worst evil,
privatized reproduction(parenting):
it is the primary source of drug abuse, drug wars,
schizophrenia(mass rejection), and mass murder .]
. that realization
gave me this spin of the genesis story:
. god insists nothing should be private:
(genitals should remain in public view)
but after Adam's snake gave Eve
that first taste of fruiting
-- a harsh labor, and countless childhood emergencies --
they both decided it would be best if they
put all their troublesome differences out of sight .
. that, of course,
was the end of the first perfect garden .
. slavery is also a constant theme in the bible:
we have to put fig leaves between
the poor and the rich,
the mgt and labor,
your parenting style vs mine .
. the genesis author's god was right:
things should be specialized,
and things should not be private .
. secrets are not sure security,
but they are a sure source of power abuse .
. we should be able to inspect and have a say in
all things that can have an influence on us .
. I'm not saying that's an enforceable rule,
but it's where perfected technology is heading,
simply because that technology by definition
will make such per-module omniscience possible;
that is, it can enforce separate environments
and enable awareness of everything in
one's own environment .

se-methylselenocysteine preventing cancer

Se-methylselenocysteine -- at iherb and amazon--
is a uniquely non-toxic form of selenium,
the essential mineral;
I've routinely taken 20doses a day
-- that's 4mg*... (that would be too toxic in other forms).
. here are more references to articles about
how it prevents cancer, and maybe old-age blindness
(this will be added to my selenium knol).

12.12: web.health/se/se-methylselenocysteine:
TRAIL (TNF-Related Apoptosis-Inducing Ligand)
International Journal of Oncology May 2009 Volume 34 Number 5

. Se-MSC rapidly and specifically down-regulates
expression of the Bcl-2 at transcriptional level.
The forced expression of Bcl-2
attenuated Se-MSC plus TRAIL-mediated apoptosis,
suggesting that Se-MSC's reduction of Bcl-2 expression
is critical to the increased sensitivity
to TRAIL in renal cancer cells.
In addition, we demonstrate that the synergistic effects
of Se-MSC and TRAIL
result from the activation of the
caspase-dependent pathways.
Co-administration of HA14-1,
a small molecule Bcl-2 inhibitor
and TRAIL increased apoptosis in Caki cells.
Taken together, Se-MSC-mediated down-regulation of Bcl-2
is able to sensitize Caki cells for
TRAIL-induced apoptosis.

Programmed Cell Death

Programmed cell death (PCD), or apoptosis,
can be triggered by a wide range of stimuli,
including cell surface receptors like Fas
or tumor necrosis factor receptor 1 (TNFR1).
It constitutes a system for the removal of
unnecessary, aged, or damaged cells
. the relative abundance of
proapoptotic and antiapoptotic proteins
determines the susceptibility of the cell
to programmed death.

The proapoptotic proteins Bax, Bad, Bid, Bik, and Bim
contain an a-helical BH3 death domain
that fits the hydrophobic BH3 binding pocket
on the antiapoptotic proteins Bcl-2 and Bcl-xL,
forming heterodimers that block
the survival-promoting activity of Bcl-2 and Bcl-xL.

. things that result in more pro-apopt's
include: growth factor withdrawal
, genotoxic insult
, uv irradiation,
-- this reminds that chronically high
insulin (a growth factor)
can reduce one of your own sources of pro-apopt's .

The proapoptotic proteins act at
the surface of the mitochondrial membrane
to decrease the mitochondrial transmembrane potential
and promote leakage of cytochrome c.
In the presence of dATP,
cytochrome c complexes with and activates Apaf-1.
Activated Apaf-1 binds to downstream caspases,
such as pro-caspase-9,
and processes them into
proteolytically active forms.
This begins a caspase cascade
resulting in apoptosis.

Smac/Diablo is released from the mitochondria
and blocks IAP proteins that normally interact with
caspase-9 to inhibit its conversion to
the apoptosis-effecting caspases-{3, 6, 7}

The graphic shows the conserved apoptotic pathway
in the organism C. elegans .
CED-3 encodes a caspase whose function is facilitated by CED-4,
which is highly similar to Apaf-1.
CED-4 function is blocked by CED-9,
which protects cells against apoptosis
and is similar to the human antiapoptotic protein Bcl-2.
CED-9 activity is inhibited by EGL-1,
which is similar to the proapoptotic Bcl-2 family members.

Se-methylselenocysteine inhibits
phosphatidylinositol 3-kinase activity
Breast Cancer Res (2005) 7: R699-707

Se-methylselenocysteine (MSC),
a naturally occurring selenium compound,
is a promising chemopreventive agent
against in vivo and in vitro models of
carcinogen-induced mouse and rat mammary tumorigenesis.
We have demonstrated previously that MSC
induces apoptosis after a cell growth arrest in S phase
in a mouse mammary epithelial tumor cell model (TM6 cells) in vitro.
The present study was designed to examine the involvement of
the phosphatidylinositol 3-kinase (PI3-K) pathway
in TM6 tumor model in vitro after treatment with MSC.
RESULTS: PI3-K activity was inhibited by MSC
followed by dephosphorylation of Akt.
The phosphorylation of p38 MAPK was also downregulated
after these cells were treated with MSC.
In parallel experiments MSC inhibited the
Raf-MEK-ERK signaling pathway.
CONCLUSION:
These studies suggest that MSC blocks
multiple signaling pathways
in mouse mammary tumor cells.
MSC inhibits cell growth by inhibiting the activity of PI3-K
and its downstream effector molecules
in mouse mammary tumor cells in vitro.

Se-methylselenocysteine (MSC) chemically synthesized:
. [these 2 ref's were given]:
# SYNTHESIS OF [TRIMETHYLSELENONIUM-SE-75 IODIDE
FROM [SELENOCYSTINE-SE-75]
Source: ANALYTICAL BIOCHEMISTRY Volume: 137 Issue: 1 Pages: 205-209
Published: 1984 Reprint Address: FOSTER, SJ (reprint author),
UNIV WISCONSIN, DEPT NUTR SCI, MADISON, WI 53706 USA
ISSN: 0003-2697
# Chemical Form of Se,
Critical Metabolites, and Cancer Prevention:

Methylated selenides are prominent metabolitesat the dietary levels
used for obtaining anticarcinogenic effects with selenium.
The present study reports the chemopreventive activities
of 2 novel selenium compounds,
Se-methylselenocysteine and
dimethyl selenoxide,
Other treatment groups were supplemented with either
selenite or selenocystine for comparative purposes.
Results of the carcinogenesis experiments showed that
the relative efficacy with the four compounds was
Se-methylselenocysteine > selenite
> selenocystine > dimethyl selenoxide.
In correlating the chemical form
and metabolism of these selenium compounds
with their anticarcinogenic activity,
it is concluded that:
(a) selenium compounds that are able to generate
a steady stream of methylated metabolites,
particularly the monomethylated species,
are likely to have good chemopreventive potential;
(b) anticarcinogenic activity is lower for selenoamino acids,
such as selenocysteine following conversion from selenocystine,
which have an escape mechanism via
random, nonstoichiometric incorporation into proteins;
(c) forms of selenium, as exemplified by
dimethyl selenoxide,
which are metabolized rapidly and quantitatively
to dimethyl selenide and trimethylselenonium
and excreted,
are likely to be poor choices.
We also undertook a separate bioavailability study
using
Se-methylselenocysteine
, dimethyl selenoxide
, and trimethylselenonium
as the starting compounds for delivering selenium with
one, two, or three methyl groups,
and measured the ability of these compounds to restore
glutathione peroxidase activity in selenium-depleted animals.
All three compounds were able to
fully replete this enzyme,
although with a wide range of efficiency
(Se-methylselenocysteine >
dimethyl selenoxide > trimethylselenonium),
suggesting that complete demethylation
to inorganic selenium
is a normal process of selenium metabolism.
However, the degree to which this occurs
under chemoprevention conditions
would argue against the involvement of selenoproteins
in the anticarcinogenic action of these selenium compounds.

-- Sodium selenite was obtained from
Sigma Chemical Co. (St Louis, MO, USA).
--. wholesaler only:
but they do have Se-methylselenocysteine:
M6680 Sigma Se-(Methyl)selenocysteine hydrochloride 95% (TLC)

CAS Number: 863394-07-4
Empirical Formula (Hill Notation): C4H9NO2Se · HCl
Molecular Weight: 218.54
MDL number: MFCD03412450
PubChem Substance ID: 24278564
Description: Se-(Methyl)selenocysteine
. a chemopreventive agent that blocks
cell cycle progression and proliferation of
premalignant mammary lesions;
and, induces apoptosis of cancer cell lines in culture.
M6680-100MG /$ 164.50

Sigma-Aldrich Corp
St. Louis, MO, USA
Phone: 314-771-5765, Fax: 314-771-5757
E-mail: OC_DOM_HC@sial.com
Ordering & Customer Service
Phone: 800-325-3010

# Opening a Sigma-Aldrich Account
Accounts are generally established for a company or institution
rather than for individuals.
# Your business or institution must have an established
Customer Account with Sigma-Aldrich
to establish an account, and be approved for on-line ordering;
you will need to contact Support by phone.
You cannot establish an account on-line.

12.12: news.health/se/se-methylselenocysteine/Protease inhibitors:
Protease inhibitors suppress apoptotic features induced by MSC

These results confirm previous observations
that caspase-3 is crucial for inducing apoptosis by MSC treatment,
and further suggest the possibility that
an unknown member of the serine protease family
is involved in MSC-mediated apoptosis.
Our results strengthen the possibility that
MSC can be used to prevent or cure cancer
as either a chemopreventive or a chemotherapeutic agent.
Further studies are required to differentiate between
the chemopreventive effects on normal cells
and cancer cells in vitro.

12.26: health/se/age-related macular degeneration:

I lamented how mom's eyes still got cataracts
even with supplemental selenium
-- not because selenium is quack
but because of
stress-induced melatonin disfunction
not allowing the selenium to be useful;
and now hearing about macular degeneration
I found only one article saying it helps that
when I know it helps so much more
(anti-cancer, anti-heart disease)
because of the way it enables selenium!

. in answering the question:
Does melatonin have any bad side effects
in someone mom's age?

here's something that starts as a warning
"(replacement of melatonin just for being elderly
is not recommended)
but actually becomes a great encouragement:
Although elderly people often have difficulty sleeping
it's not from being elderly
but from being either emotionally ill
(making too many stress hormones
that suppress melatonin secretion)
or using drugs that suppress melatonin secretion
(e.g., aspirin, ibuprofen, beta-blockers).
Adults with insomnia, heart disease, or schizophrenia
routinely have lower melatonin levels.

I found this study ok'ing elderly women 64 to 80 years
(it measures cortisol and dhea!)

Effects of six months melatonin treatment
on sleep quality and "serum concentrations of
estradiol, cortisol, dehydroepinadrosteron sulfate,"
and somatomedin C in elderly women
M. Pawlikowski, M. Kolomecka, A. Wojtczak & M. Karasek:
October 9 , 2002 NEUROENDOCRINOLOGY LETTERS

CONCLUSIONS:
On the basis of this preliminary open study
it seems that melatonin administration
may be beneficial for elderly subjects.
A significant decrease of estradiol concentrations
was observed after 6 months of the melatonin treatment
in comparison to initial levels.
IGF-I was found to be slightly but significantly
increased after the 6 months melatonin therapy.
Cortisol levels did not change significantly,
during the melatonin treatment.
DHEAS concentrations increased
after melatonin therapy.
-- a higher DHEAS/cortisol ratio .
Melatonin treatment did not influence significantly
either the parameters of total blood count
or glucose and serum lipids levels.
OBJECTIVES:
The role of melatonin in aging
is still under debate.
Therefore, an open pilot study on the effects of melatonin
was performed in elderly women.
SUBJECTS AND METHODS:
The study was performed on 14 women (volunteers),
aged from 64 to 80 years (mean age 71±4.6 years).
Melatonin (2 mg daily at 19:00 h) was administered during 6 months.
Before and after melatonin treatment
the peripheral venous blood samples
were taken in the morning (approx. at 08:00 h)
after the overnight fast.
The total blood count, glucose, total cholesterol,
LDL, HDL, and triglycerides were estimated by
routine laboratory methods.
The serum concentrations of the following hormones
were determined: 17-beta-estradiol,
dehydroepiandrosterone sulfate (DHEAS),
cortisol, and somatomedin C (IGF-I).

12.26: web.health/se/macular degeneration/se's role:
links from i-care:

# Glutathione and its related enzyme precursor amino acids
(N-Acetyl-Cysteine, L-glycine and glutamine,
as well as selenium)
are protective against damage to
human retinal pigment epithelium cells,
and may help prevent retinal damage in AMD.
Invest Ophthalmol Vis Sci 1993 Dec;34(13):3661-8
# Consumption of fruits and vegetables is protective against
progression of macular degeneration.
Cho, Seddon, et al Arch Ophthalmol. 2004 Jun;122(6):883-92
# In a clinical trial 60% of subjects with ARMD
or diabetic macular edema [...] So Med J, 1987.

[. interesting term: diabetic macular edema
had me convinced that metabolic disorder
-- caused from the use of carb's
by carb'intolerant elders --
was the primary reason elders were getting armd .
so another source of damage besides
not getting the se to the gluthione peroxidase
is not having the circulation for
getting the glutathione to the retina .]

care for high-risk elders

2.10: co.health/care for high-risk elders:
Health and Wellness Product Information Group
Are you and your agency prepared to work with
lesbian and gay seniors?

my reply:

. according to that article,
sexual minorities have a lot in common with
the mentally ill: fewer social connections,
and thereby a greater risk of stress conditions .
. they should be reminded to compensate by
concentrating on the other branches of longevity:
#: finding self-employment you love,
both challenging and providing a feeling of flow .
#: staying on a disciplined diet
that keeps hormones in the zone:
beans, greens, yams, and no grains or sugar .
#: peak resistance exercise
for maximizing natural growth hormone .

the state of psychiatry on scifri.com

12.18: news.psy/the state of psychiatry on scifri.com:

. the most painful part of the job being the intake or

triage psychiatrist at a major city's mental hospital

was rooting out malingerers (sharks)

Malingering is a medical term that refers to exaggerating

the symptoms of mental or physical disorders

for a variety of "secondary gain" motives,

which may include financial compensation (often tied to fraud);

avoiding school, work or military service;

obtaining drugs; getting lighter criminal sentences;

or simply to attract attention or sympathy.

Legally, it is often referred to as fabricated mental illness

or feigned madness .

-- very common as homelessness or struggles increase .

very bad for patients ? is that a tele'bullying thing?

or just the fact they need to be tight with services?

. one assistant caller noticed that m'illness was catchy,

. when m'ill are packed together they can feed off each other's illnesses

(not a shark-specific problem);

the ref' was to why the doctor needed a break ?

. in her last interview she said she had to break because

of taking care of small children;

at the time I first heard that,

I got the idea her problem was that

she would have this tele'relation with patients

that seemed to follow her to her children's relationship .

. she did have to admit her profession was an ill bunch:

they always have m'ill in self or close relative .

. mdma (ecstasy) may help talk therapy,

and as 1st-line defense in schiz'ic crisis .

. pot and shrooms, too, may have medical potential,

but she points out that the laws affecting rec'drugs

are also inhibiting scientific experimentation

that could disprove these drugs have no medical value .

. the laws are definitely more a fear of the supernatural-religious

than any scientific-medical basis .

. pot could help schiz'ia?

that does mesh well with other data:

things that help a symptom

will tend to cause that symptom during withdrawal .

. often schiz'ic onset occurs shortly after

making a commitment to avoid one's prior life

as are situations of trying to change social class

(esp'ly from a lower to a higher status) .

. what's the best way to get into psych'?

psy.D takes 7yrs, but md with psychopharm specialty takes only 4 .

. another way is medical assistant .

homelessness

8.3: pol/homelessness:

. I wonder why nobody is addressing the fact that

the bulk of homeless are really people with bad reputations,

being encouraged to fester in our jungles .

. they present them as being mentally ill,

but retiring from a life of crime is a huge culture shift

-- this is the stuff that makes symptoms of mental illness .

. this treatment was what gave birth to the charles manson clan .

virtually true delusions

8.17: psy/schiz'ia/virtually true delusions:

. delusions that involve persecution by large groups of people?

that could be virtually true,

as everything that is those people

has to come through your mind before it can get to you .

. your mind literally invents everything;

ie, if it wants everyone to be your nightmare,

they will be -- they can not be anything else .

. recreational drugs can make them irrelevant,

and anti-psychotic drugs can make you irrelevant,

but there is no changing who your mind says they are .

medical model for schizophrenia

6.6: todo.co.psy/schiz'ia/dopamine theory:

. if anyone who had money cared about schiz'ia,

they would take the psychiatric society to court,

asking where they get the idea

that schiz'ics have a dopamine excess .

"( . well, if they settle down after a dopamine reduction ...

)

. yea, well, raving freedom fighters settle down too!

so what? .

6.25: careers in psych:

"(

Unfortunately, prejudice and discrimination

against the mentally ill still exists.

Sometimes this stigma is also directed against

those who care for the mentally ill.

Occasionally, even our colleagues in medicine

are unaware that

mental illnesses are real

(i.e., genetically and biochemically based)

and can be diagnosed and treated

with the same accuracy and effectiveness

as other medical illnesses.

) .

6.25: psych.org`maximizing pharm in schiz'ia:

MAXIMIZING PHARMACOTHERAPY IN THE TREATMENT OF

SEVERE AND PERSISTENT MENTAL ILLNESS:

The Case for Maintaining Open Access to

Medically Indicated Medications for Schizophrenia

. The Office of Healthcare Systems and Financing

American Psychiatric Association

March 2004

"antipsychotics", so named for their initial use in treating

the classical psychotic delusions and hallucinations associated with schizophrenia.

Today these medications are increasingly prescribed to treat

many severe and persistent mental illnesses,

among them bipolar disorder, psychotic depression,

and aggressive conduct disorders.

Indeed, for patients with schizophrenia,

limitations on access to the most effective

and appropriate medications available results

not only in incomplete recovery and potential relapse,

but carries significant risk of death

as persons with schizophrenia are at significantly higher risk of

suicide compared with the general population.

As positive symptoms decrease, the risk of self-harming behaviors

(including suicide risk) decreases

and disturbed behaviors are controlled

. after reading that, I had to ask:

"(Do Antipsychotic Drugs Influence Suicidal Behavior in Schizophrenia?)

The literature concerning the net effect of antipsychotic medication

on suicidality in patients with schizophrenia

is not consistent.

This review assesses this problem in the light of relevant research.

MEDLINE was used to search for articles written in English from 1964 to 2006

. Articles were classified according to the following three orientations:

positive, negative, or null effect on suicidality

. Several inconsistencies among the studies

and methodological difficulties appeared

and a singular conclusion on this issue was not possible.

Competing properties of various antipsychotic drugs

may have differential effects on suicidality.

Second-generation antipsychotic agents

appear to have a better potential for preventing suicide in schizophrenia,

but the relative profile of each drug is yet to be clarified.

A good profile to treat hostility, impulsivity, and depression

while not provoking extrapyramidal side effects

is crucial when choosing an antipsychotic in the presence of suicide risk.

The strongest and perhaps unique evidence

has been shown for clozapine,

which seems to have a clinically relevant advantage over both

first- and second-generation antipsychotics for reducing suicidality.

. the drugs being used for schiz'ia are also being used for

aggressive conduct disorders .

. there's no magic, these drugs plain knock the crap out of you .

"(

. for many patients with schizophrenia

and other persistent and severe mental illnesses,

it is inherently difficult for them to take their medications to begin with

. Some estimates say as high as 70 percent to 80 percent of patients with schizophrenia

do not take their medications as directed by their physicians.

The reasons are numerous and complex, including patients' poor insight,

cognitive deficits

and mood symptoms that are part of the disease process.

Also high on the list of significant barriers to

patients consistently taking their medications

are the often significant side effects

associated with antipsychotic medications.

) -- March 2004 ? American Psychiatric Association Page 5

. how could clozapine be an improvement?

when they don't make you feel like crap,

they are literally killing you with kindness:

creating a feeling of well-being by raising blood sugar

and creating the same risks presented by diabetes .

"(

Assessment for medical causes of a patient's symptoms of psychosis

is especially important because numerous medical conditions

may present with psychosis, including Cushing's syndrome,

epilepsy, brain tumors, traumatic brain injury,

and metabolic disorders .

)

--. this gave me the idea that some of the diff's in types of schiz'ia

may be due to the schiz'ic process causing various degrees of stress

which in turn cause various degrees of metabolic disorder

(eg, blood sugar that is too low) .

(Zyprexa) in 1996, quetiapine (Seroquel) in 1997,

and ziprasidone (Geodon) in 2001.

With the introduction of aripiprazole (Abilify) late in 2002,

the third generation of antipsychotics was born.

The single third-generation drug works through a significantly different mechanism:

partial agonism at D2 receptors. [rather than

full antagonism]

As a partial agonist, when levels of dopamine are high,

aripiprazole blocks dopamine receptors, reducing dopaminergic activity.

When levels of dopamine are low, the drug boosts the sensitivity of the receptors

to the dopamine that is available.

The same relationship is true for aripiprazole's interaction with

specific types of serotonin receptors.

As a result, some refer to the drug as a dopamine/serotonin system stabilizer.

An emerging theory proposes that

blockade of dopaminergic activity at D2 receptors specifically within the

meso-limbic area of the brain Ð known as the A10 dopaminergic tracts Ð

is related to antipsychotic action.

Binding to D2 receptors in other areas of the brain

is related to side effects,

such as EPS and increased levels of the hormone prolactin.

A substantial body of research now indicates

that each of the available second-generation antipsychotic medications,

as well as the first of the third-generation medications,

has been proven to possess clinically significant differences

from the other medications within the therapeutic class.

Individual patients' response to different medications is variable,

as is the risk of side effects.

Therefore, it is absolutely critical that physician's closely match

a specific medication to each individual patient's needs.

in 2003, the U.S. FDA approved a formal indication for clozapine

for the treatment and prevention of suicidal ideation and behaviors.

--

. has anyone been able to use clozapine

without adversely affecting blood lipids

(as an indicator of metabolic disorder

and a predictor of heart disease) ?

perhaps it's suicide either way:

it doesn't matter if the suicide was nipped,

since statistically that drug is sure to be a homicide .

according to

Kaplan & Sadock's concise textbook of clinical psychiatry

80% of alcohol-dependent suicides

and the subgroup of depressives most likely to suicide

belong to males during middle-age

that are unmarried, friendless, and socially isolated .

. this is the primary subgroup of the suicidal schiz'ics too,

but at a younger age .

. these are termed egoistic suicides,

being preceded by social death .

. generally the key is hopelessness:

suicide is higher among professionals,

and this may be that there's more reasons forcing one to step down,

while at the same time,

being that high make one prefer stepping out to stepping down .

psychlaws.org/briefingpapers/BP6.htm+suicide+medication+schizophrenia+rates

* Estimates of the completed suicide rate for individuals with schizophrenia

range from 10 to 13 percent.

Caldwell C and Gottesman I. Schizophrenics kill themselves too:

a review of risk factors for suicide. Schizophrenia Bulletin 16:571-589, 1990.

* This rate is at least four times higher than

similar studies from the period from 1913 to 1960,

suggesting that the suicide rate has risen markedly since

massive deinstitutionalization began.

Stephens J et al.

Suicide in patients hospitalized for schizophrenia: 1913-1940.

Journal of Nervous and Mental Disease 187:10-14, 1999.

* A case control study of 63 individuals with schizophrenia

who committed suicide and 63 individuals with schizophrenia who did not

reported that "there were seven times as many patients who

did not comply with treatment in the suicide group

as there were in the control group."

De Hert M et al.

Risk factors for suicide in young people suffering from schizophrenia:

a long-term follow-up study.

Schizophrenia Research 47:127-134, 2001.

--

. after reading that,

it occured to me that they had a case of selection bias:

. the one's who were "(willing) to be medicated,

were doing so against their will;

ie, they would be punished for not doing so;

and those who did commit suicide

had actually been pushed into suicide by meds;

ie, you can either be tortured by this mommy-dearest meds treatment,

or you can step out .

. another hypothetical situation

would simply make the meds irrelevant:

when things are hopeless eno' to take your own life,

you're exactly the one who's less likely to

comply with others' demands .

* Studies have suggested that some antipsychotic medications,

and especially lithium, may decrease the incidence of suicide

among individuals with severe psychiatric disorders.

Tondo L et al.

Lithium and suicide risk in bipolar disorder.

Primary Psychiatry 6:51-56, 1999.

* A Swiss 34-year follow-up study of 158 individuals with bipolar disorder

reported that 18 of them (11 percent) had committed suicide.

The suicide rate was more than twice as high among

patients who had not been treated

compared to those who had been treated (p = 0.04),

a difference the authors called Òspectacular.Ó

Angst F, Stassen HH, Clayton PJ et al.

Mortality of patients with mood disorders: follow-up over 34-38 years.

Journal of Affective Disorders 68:167-181, 2002.

8.25: psy/religion is not delusional:

. the dsm gives specific examples of non-provable things

that are proof of delusion;

but gives exception to cases where the delusional people

happen to be agreeing with their culture's religious beliefs .

. the main point of this

is not to cast a shadow on religion as being delusional;

rather, it is giving perspective or context

to the intent of the definition:

. we are concerned about giving a diagnostic label to

disorders involving delusion;

whereas, religiously or culturally sanctioned delusions,

are by definition a sociable, orderly act .

10.27: todo.psy/schiz'ia/the science of policy:

. in the current theory

that discounts spiritual or telepathic communications

there is no way to differentiate

a schiz'ic hearing voices of being yelled at

from those who stay quiet about such yelling

due to an understanding that

it's a private domestic dispute

or it's a vigilante action against one who broke a taboo .

11.13: news.psy/metapsychology.mentalhelp.net:

. metapsychology.mentalhelp.net gets a bad review from mywot.com:

. here is a Review of Doctoring the Mind: Is Our

Current Treatment of Mental Illness Really Any Good?

While a lot of criticism of psychiatry's approach

has recently come from within the profession itself,

stopping short of criticizing psychiatry itself, Bentall, a psychologist,

and a Professor at Bangor University in the UK,

takes on psychiatry for its failure to improve the mental health of nations

since its entry into the world of intervention.

Bentall is part of the antipsychiatry movement

whose first major players, Cooper, Laing, Szasz

were themselves disillusioned psychiatrists,

although their reasons and styles were different.

This does not mean he is against psychiatry:

like Miller and others he is merely questioning the way it all works.

Or rather, doesn't .

bone of contention that psychiatric nurses with psychologists

Doctoring the Mind by Richard P Bentall (Hardcover - 25 Jun 2009) review

I work as a psychiatric nurse on a intensive care ward

and have often been in the centre of power struggles

between psychologists and psychiatrists.

From my experience,

Psychologists seem to believe in the ubiquitous efficacy

of dialectical/cognitive behaviour therapy

as a treatment for severe mental illness.

For example, mindfulness meditation

as a treatment option for Bipolar Affective Disorder.

Psychiatrists spend 10 minutes a week with patients

and take a medical model approach eg, assessment, diagnosis and treatment.

However in fairness,

psychologists spend even less time with inpatients.

The bone of contention that psychiatric nurses have with psychologists

involves their inability to understand the concept of risk

and consequently risk management.

They only promote the therapeutic interactions.

Sometimes however, nurses have to manage risk

which sometimes involve difficult and dangerous situations.

However, often nurses are blamed for the patients acting out behaviour

due to insufficient therapeutic skill.

This often causes burn out in nurses

and leads to a profession feeling devalued.

my response:

. the real bone of contention that psychiatric nurses have

is not with psychologists but with politicians .

. there are young patients on many wards,

including intensive care units,

for nothing more than being a drug abuser

and an authority fighter

-- basically a product of grossly asocialized parenting .

. the line we draw between criminals and psychotics

is ludicrous;

and being a psychiatric nurse is really all about

taking these obvious criminals

and beating them into submission

in such a civilized way, with drugs

that actually cause such hormonal imbalance

as to knock all the fight out of the aggressors .

. there's no more burn-out in psychiatric nurses

than there is in prison guards:

it's the same stupid work,

giving the same aweful result !

. this is why the psychiatrist is your best friend,

medications are a prison guard's best friend .

. if we had all the money we wanted,

we could give the self-abusive mind

a nice isolation unit,

perhaps some pleasant recreational drugs,

or whatever good money can think of;

and, if they still continued to abuse themselves

then let them go wherever self-abuse takes them .

. this sad conclusion

is where the psychologist is your best friend:

they have the science that may help us

with prevention of self-abuse and crime

rather than this ridiculously ineffective patching-up

of the social suicides .

11.14: web.psy/books about pschiatry being self-critical:

. notice books similar to recent: ...

Doctoring the Mind: Is Our Current Treatment of Mental Illness Really Any Good?

by Richard P. Bentall

by Thomas Stephen Szasz (psychiatrist):

Coercion as Cure: A Critical History of Psychiatry

The Medicalization of Everyday Life: Selected Essays

The Myth of Psychotherapy: Mental Healing As Religion, Rhetoric, and Repression

The Myth of Mental Illness: Foundations of a Theory of Personal Conduct (Revised Edition)

Psychiatry: The Science of Lies

Szasz Under Fire: The Psychiatric Abolitionist Faces His Critics

by Ph.D. Jeffrey A. Schaler (Editor)

Ethics of Psychiatry: Insanity, Rational Autonomy, and Mental Health Care

by Rem B. Edwards (Editor)

The Medicalization of Society:

On the Transformation of Human Conditions into Treatable Disorders

by Peter Conrad

Toxic Psychiatry: Why Therapy, Empathy and Love Must Replace

the Drugs, Electroshock, and Biochemical Theories of the "New Psychiatry"

by Peter Roger Breggin

Blaming the Brain: The Truth About Drugs and Mental Health

by Elliot Valenstein (Author)

Rethinking Psychiatric Drugs: A Guide for Informed Consent

by Grace E. Jackson

The Myth of the Chemical Cure: A Critique of Psychiatric Drug Treatment

by Joanna Moncrieff

11.27: pol/dr.psychi/is someone chasing you?:

. going from lobotomy being unpopular

to meds that lobotomize discretely,

by testing the drugs for short durations;

and, then insisting that the meds only work with sustained use

which is followed by the unfortunate sideaffect

of frontal atrophy .

. but doesn't dr.psychi really medicate our culture's

secret addiction ?

that of always being chased by a weakness for

money-burning overpopulationism ?

. sanity is god's way of saying

I want more of this ...

where's the army of homeless coming from?

has-beens (mental, criminal, ... untrustable or taboo).

. it's not ok to encourage suicide,

but is ok to encourage tb and other diseases?

have you seen the cost of housing inmates in isolation

-- no need for guards that would be more inhumane

can't possibly work for all this musical chairs sweatiness,

insanity might be god's too ?

other behaviors ?